Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 559956..560187 Replicon chromosome
Accession NZ_CP124442
Organism Escherichia coli strain AVS0196

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 559957..560059 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 559956..560187 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJP94_RS02900 557154..557963 + 810 WP_000166317.1 recombination protein RecT -
QJP94_RS02905 558020..558214 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
QJP94_RS02910 558207..558395 + 189 WP_001356607.1 DUF1187 family protein -
- 558213..558391 - 179 NuclAT_0 - -
- 558213..558391 - 179 NuclAT_0 - -
- 558213..558391 - 179 NuclAT_0 - -
- 558213..558391 - 179 NuclAT_0 - -
QJP94_RS02915 558502..558783 + 282 WP_001311878.1 excisionase -
QJP94_RS02920 558749..559825 + 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
- 559956..560187 + 232 - - Antitoxin
- 559957..560059 - 103 - - Toxin
QJP94_RS02925 560217..560558 - 342 WP_000976472.1 YebY family protein -
QJP94_RS02930 560571..561443 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
QJP94_RS02935 561447..561821 - 375 WP_000168747.1 CopC domain-containing protein YobA -
QJP94_RS02940 561960..562190 + 231 WP_000916763.1 DNA polymerase III subunit theta -
QJP94_RS02945 562292..562948 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QJP94_RS02950 562972..563634 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 514559..565691 51132
- inside Prophage - - 509178..567242 58064


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T280282 NZ_CP124442:c560059-559957 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT280282 NZ_CP124442:559956-560187 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References