Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 86960..87519 | Replicon | plasmid pAVS0465-A |
Accession | NZ_CP124368 | ||
Organism | Escherichia coli strain AVS0465 |
Toxin (Protein)
Gene name | relE | Uniprot ID | V0SVC8 |
Locus tag | QJP75_RS25935 | Protein ID | WP_000421272.1 |
Coordinates | 86960..87235 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | V0SRR3 |
Locus tag | QJP75_RS25940 | Protein ID | WP_001387467.1 |
Coordinates | 87235..87519 (-) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP75_RS25900 (82134) | 82134..83156 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
QJP75_RS25910 (84141) | 84141..84409 | - | 269 | Protein_99 | type II toxin-antitoxin system RelE/ParE family toxin | - |
QJP75_RS25915 (84396) | 84396..84664 | - | 269 | Protein_100 | type II toxin-antitoxin system ParD family antitoxin | - |
QJP75_RS25920 (85196) | 85196..86365 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
QJP75_RS25925 (86398) | 86398..86526 | + | 129 | Protein_102 | IS481 family transposase | - |
QJP75_RS25930 (86651) | 86651..86854 | - | 204 | Protein_103 | hypothetical protein | - |
QJP75_RS25935 (86960) | 86960..87235 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QJP75_RS25940 (87235) | 87235..87519 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
QJP75_RS25945 (88124) | 88124..88876 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
QJP75_RS25950 (88922) | 88922..89887 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
QJP75_RS25955 (89920) | 89920..90300 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
QJP75_RS25960 (90325) | 90325..91215 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
QJP75_RS25965 (91448) | 91448..91642 | - | 195 | WP_000796505.1 | hypothetical protein | - |
QJP75_RS25970 (91616) | 91616..92056 | + | 441 | Protein_111 | zinc-binding dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | qacE / sul1 / mph(A) / dfrA17 / blaCTX-M-15 / blaOXA-1 / aac(6')-Ib-cr | - | 1..103076 | 103076 | |
- | flank | IS/Tn | - | - | 83410..83913 | 503 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | V0SVC8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0Y880 |