Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 3661071..3661647 | Replicon | chromosome |
Accession | NZ_CP124367 | ||
Organism | Escherichia coli strain AVS0465 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | A0A061KXE4 |
Locus tag | QJP75_RS17770 | Protein ID | WP_001295743.1 |
Coordinates | 3661071..3661358 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A066STF6 |
Locus tag | QJP75_RS17775 | Protein ID | WP_000063148.1 |
Coordinates | 3661345..3661647 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP75_RS17755 (3656731) | 3656731..3658035 | - | 1305 | WP_000535012.1 | restriction endonuclease subunit S | - |
QJP75_RS17760 (3658025) | 3658025..3659644 | - | 1620 | WP_001029745.1 | class I SAM-dependent DNA methyltransferase | - |
QJP75_RS17765 (3659708) | 3659708..3660874 | - | 1167 | WP_000800831.1 | restriction endonuclease | - |
QJP75_RS17770 (3661071) | 3661071..3661358 | + | 288 | WP_001295743.1 | BrnT family toxin | Toxin |
QJP75_RS17775 (3661345) | 3661345..3661647 | + | 303 | WP_000063148.1 | BrnA antitoxin family protein | Antitoxin |
QJP75_RS17780 (3661681) | 3661681..3662637 | - | 957 | WP_001295745.1 | GTPase | - |
QJP75_RS17785 (3662648) | 3662648..3662851 | - | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
QJP75_RS17790 (3662901) | 3662901..3665051 | - | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A061KXE4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A066STF6 |