Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1890203..1890857 Replicon chromosome
Accession NZ_CP124355
Organism Escherichia coli strain AVS0171

Toxin (Protein)


Gene name cptA Uniprot ID F4T2L4
Locus tag QJB00_RS09400 Protein ID WP_000244765.1
Coordinates 1890203..1890610 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID F4T2L5
Locus tag QJB00_RS09405 Protein ID WP_000354050.1
Coordinates 1890591..1890857 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJB00_RS09380 (1886160) 1886160..1887893 - 1734 WP_000813195.1 single-stranded-DNA-specific exonuclease RecJ -
QJB00_RS09385 (1887899) 1887899..1888609 - 711 WP_000715230.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QJB00_RS09390 (1888634) 1888634..1889530 - 897 WP_000806638.1 site-specific tyrosine recombinase XerD -
QJB00_RS09395 (1889642) 1889642..1890163 + 522 WP_001055874.1 flavodoxin FldB -
QJB00_RS09400 (1890203) 1890203..1890610 - 408 WP_000244765.1 protein YgfX Toxin
QJB00_RS09405 (1890591) 1890591..1890857 - 267 WP_000354050.1 FAD assembly factor SdhE Antitoxin
QJB00_RS09410 (1891100) 1891100..1892080 + 981 WP_000886084.1 tRNA-modifying protein YgfZ -
QJB00_RS09415 (1892157) 1892157..1892816 - 660 WP_000250275.1 hemolysin III family protein -
QJB00_RS09420 (1892980) 1892980..1893291 - 312 WP_001182956.1 N(4)-acetylcytidine aminohydrolase -
QJB00_RS09425 (1893336) 1893336..1894769 + 1434 WP_001296350.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 16043.95 Da        Isoelectric Point: 11.5202

>T279777 WP_000244765.1 NZ_CP124355:c1890610-1890203 [Escherichia coli]
VVLWQSDLRVSWRAQWLSLLIHGLVAAVILLIPWPLSYTPLWMVLLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQ
EWSIVKAPWMIKSGMMLRLRSDSGKRQHLWLAADSMDEAEWRDLRRILLQQETQR

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10535.07 Da        Isoelectric Point: 5.1599

>AT279777 WP_000354050.1 NZ_CP124355:c1890857-1890591 [Escherichia coli]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRTFIRLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A454A7D7

Antitoxin

Source ID Structure
AlphaFold DB A0A061L3F4

References