Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 3770028..3770604 | Replicon | chromosome |
Accession | NZ_CP124349 | ||
Organism | Escherichia coli strain AVS0453 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | A0A061KXE4 |
Locus tag | QJP64_RS18540 | Protein ID | WP_001295743.1 |
Coordinates | 3770028..3770315 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A066STF6 |
Locus tag | QJP64_RS18545 | Protein ID | WP_000063148.1 |
Coordinates | 3770302..3770604 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP64_RS18525 (3765688) | 3765688..3766992 | - | 1305 | WP_000535012.1 | restriction endonuclease subunit S | - |
QJP64_RS18530 (3766982) | 3766982..3768601 | - | 1620 | WP_001029745.1 | class I SAM-dependent DNA methyltransferase | - |
QJP64_RS18535 (3768665) | 3768665..3769831 | - | 1167 | WP_000800831.1 | restriction endonuclease | - |
QJP64_RS18540 (3770028) | 3770028..3770315 | + | 288 | WP_001295743.1 | BrnT family toxin | Toxin |
QJP64_RS18545 (3770302) | 3770302..3770604 | + | 303 | WP_000063148.1 | BrnA antitoxin family protein | Antitoxin |
QJP64_RS18550 (3770638) | 3770638..3771594 | - | 957 | WP_001295745.1 | GTPase | - |
QJP64_RS18555 (3771605) | 3771605..3771808 | - | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
QJP64_RS18560 (3771858) | 3771858..3774008 | - | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A061KXE4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A066STF6 |