Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2721505..2721706 Replicon chromosome
Accession NZ_CP124121
Organism Enterobacter hormaechei strain 2020CK-00198

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2721510..2721613 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2721505..2721706 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QIW35_RS12925 (QIW35_12925) 2716721..2716981 - 261 WP_039270557.1 hypothetical protein -
QIW35_RS12930 (QIW35_12930) 2716965..2717249 - 285 WP_039270555.1 phage holin family protein -
QIW35_RS12935 (QIW35_12935) 2717389..2717586 - 198 WP_127850788.1 hypothetical protein -
QIW35_RS12940 (QIW35_12940) 2717616..2718050 - 435 WP_039270553.1 hypothetical protein -
QIW35_RS12950 (QIW35_12950) 2719496..2720011 - 516 WP_039270551.1 hypothetical protein -
QIW35_RS12955 (QIW35_12955) 2720244..2720657 - 414 WP_052685510.1 bacteriophage antitermination protein Q -
QIW35_RS12960 (QIW35_12960) 2721047..2721421 + 375 Protein_2531 tyrosine-type recombinase/integrase -
- 2721505..2721706 + 202 - - Antitoxin
- 2721510..2721613 - 104 - - Toxin
QIW35_RS12965 (QIW35_12965) 2721755..2722093 - 339 WP_003859787.1 YebY family protein -
QIW35_RS12970 (QIW35_12970) 2722110..2722979 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
QIW35_RS12975 (QIW35_12975) 2722981..2723352 - 372 WP_023296802.1 CopC domain-containing protein YobA -
QIW35_RS12980 (QIW35_12980) 2723490..2723720 + 231 WP_003859784.1 DNA polymerase III subunit theta -
QIW35_RS12985 (QIW35_12985) 2723832..2724482 + 651 WP_015570289.1 carbon-nitrogen hydrolase family protein -
QIW35_RS12990 (QIW35_12990) 2724507..2725169 + 663 WP_039270549.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2705289..2727226 21937
- inside Prophage - - 2697740..2742451 44711


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T279318 NZ_CP124121:c2721613-2721510 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT279318 NZ_CP124121:2721505-2721706 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References