279314

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1452568..1453484 Replicon chromosome
Accession NZ_CP123994
Organism Bacillus inaquosorum strain M3

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QHF92_RS07150 Protein ID WP_060398450.1
Coordinates 1452738..1453484 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID G4NV07
Locus tag QHF92_RS07145 Protein ID WP_003239095.1
Coordinates 1452568..1452738 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QHF92_RS07105 (QHF92_07105) 1447648..1449417 + 1770 WP_248596976.1 terminase -
QHF92_RS07110 (QHF92_07110) 1449429..1449758 + 330 WP_060398446.1 XkdW family protein -
QHF92_RS07115 (QHF92_07115) 1449755..1449919 + 165 WP_019258164.1 XkdX family protein -
QHF92_RS07120 (QHF92_07120) 1449966..1450805 + 840 WP_060398447.1 hypothetical protein -
QHF92_RS07125 (QHF92_07125) 1450858..1451127 + 270 WP_060398448.1 hemolysin XhlA family protein -
QHF92_RS07130 (QHF92_07130) 1451140..1451403 + 264 WP_003239099.1 phage holin -
QHF92_RS07135 (QHF92_07135) 1451416..1452309 + 894 WP_060398449.1 N-acetylmuramoyl-L-alanine amidase -
QHF92_RS07140 (QHF92_07140) 1452346..1452483 - 138 WP_119913750.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QHF92_RS07145 (QHF92_07145) 1452568..1452738 - 171 WP_003239095.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
QHF92_RS07150 (QHF92_07150) 1452738..1453484 - 747 WP_060398450.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
QHF92_RS07155 (QHF92_07155) 1453594..1454595 - 1002 WP_003239093.1 inorganic phosphate transporter -
QHF92_RS07160 (QHF92_07160) 1454608..1455225 - 618 WP_003218470.1 DUF47 domain-containing protein -
QHF92_RS07165 (QHF92_07165) 1455501..1456817 - 1317 WP_060398451.1 serine/threonine exchanger -
QHF92_RS07170 (QHF92_07170) 1457203..1458153 + 951 WP_060398452.1 ring-cleaving dioxygenase -
QHF92_RS07175 (QHF92_07175) 1458254..1458399 + 146 Protein_1353 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29097.57 Da        Isoelectric Point: 4.6191

>T279314 WP_060398450.1 NZ_CP123994:c1453484-1452738 [Bacillus inaquosorum]
MLLFFQIMVWCVMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPSSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQNRLDRKDVYYDQYGKMVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6555.59 Da        Isoelectric Point: 10.8401

>AT279314 WP_003239095.1 NZ_CP123994:c1452738-1452568 [Bacillus inaquosorum]
MERAFQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G4NV07

References