Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 450374..451027 Replicon chromosome
Accession NZ_CP123993
Organism Acinetobacter baumannii strain Ab4294

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QE150_RS03015 Protein ID WP_270901074.1
Coordinates 450638..451027 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag QE150_RS03010 Protein ID WP_001288210.1
Coordinates 450374..450631 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE150_RS02990 (QE150_02990) 445890..446897 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
QE150_RS02995 (QE150_02995) 446916..447293 + 378 WP_001216380.1 50S ribosomal protein L17 -
QE150_RS03000 (QE150_03000) 447475..448965 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
QE150_RS03005 (QE150_03005) 449014..450186 - 1173 WP_001190555.1 acyl-CoA dehydrogenase family protein -
QE150_RS03010 (QE150_03010) 450374..450631 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
QE150_RS03015 (QE150_03015) 450638..451027 + 390 WP_270901074.1 hypothetical protein Toxin
QE150_RS03020 (QE150_03020) 451797..452882 + 1086 WP_000049106.1 hypothetical protein -
QE150_RS03025 (QE150_03025) 452960..453526 + 567 WP_000651536.1 rhombosortase -
QE150_RS03030 (QE150_03030) 453714..455909 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15572.94 Da        Isoelectric Point: 10.3607

>T279311 WP_270901074.1 NZ_CP123993:450638-451027 [Acinetobacter baumannii]
MINHLNFKLKYSLFSIIFQLFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT279311 WP_001288210.1 NZ_CP123993:450374-450631 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References