Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012549..2012820 Replicon chromosome
Accession NZ_CP123963
Organism Escherichia coli strain L6-21

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012679..2012782 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012549..2012820 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC817_RS09745 2009104..2009766 - 663 WP_000944256.1 exodeoxyribonuclease X -
QC817_RS09750 2009790..2010446 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
QC817_RS09755 2010548..2010778 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QC817_RS09760 2010917..2011291 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QC817_RS09765 2011295..2012167 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
QC817_RS09770 2012180..2012521 + 342 WP_000976472.1 YebY family protein -
- 2012549..2012820 - 272 - - Antitoxin
- 2012679..2012782 + 104 - - Toxin
QC817_RS09775 2012917..2013573 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
QC817_RS09780 2013574..2013765 - 192 WP_001338167.1 YebW family protein -
QC817_RS09785 2013870..2014106 - 237 WP_001338166.1 YebV family protein -
QC817_RS09790 2014224..2015663 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T279276 NZ_CP123963:2012679-2012782 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT279276 NZ_CP123963:c2012820-2012549 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References