Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 217732..218328 | Replicon | chromosome |
Accession | NZ_CP123958 | ||
Organism | Mannheimia haemolytica strain 190176 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | QH638_RS01195 | Protein ID | WP_006249776.1 |
Coordinates | 217732..217956 (+) | Length | 75 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | A0A547EKP0 |
Locus tag | QH638_RS01200 | Protein ID | WP_006249777.1 |
Coordinates | 217999..218328 (+) | Length | 110 a.a. |
Genomic Context
Location: 214938..215543 (606 bp)
Type: Others
Protein ID: WP_006249773.1
Type: Others
Protein ID: WP_006249773.1
Location: 217732..217956 (225 bp)
Type: Toxin
Protein ID: WP_006249776.1
Type: Toxin
Protein ID: WP_006249776.1
Location: 217999..218328 (330 bp)
Type: Antitoxin
Protein ID: WP_006249777.1
Type: Antitoxin
Protein ID: WP_006249777.1
Location: 218842..219042 (201 bp)
Type: Others
Protein ID: WP_006249779.1
Type: Others
Protein ID: WP_006249779.1
Location: 219095..221287 (2193 bp)
Type: Others
Protein ID: WP_006249780.1
Type: Others
Protein ID: WP_006249780.1
Location: 213613..214515 (903 bp)
Type: Others
Protein ID: WP_006249771.1
Type: Others
Protein ID: WP_006249771.1
Location: 214512..214868 (357 bp)
Type: Others
Protein ID: WP_006249772.1
Type: Others
Protein ID: WP_006249772.1
Location: 215617..217524 (1908 bp)
Type: Others
Protein ID: WP_006249774.1
Type: Others
Protein ID: WP_006249774.1
Location: 218367..218753 (387 bp)
Type: Others
Protein ID: WP_006249778.1
Type: Others
Protein ID: WP_006249778.1
Location: 221340..222125 (786 bp)
Type: Others
Protein ID: WP_006249781.1
Type: Others
Protein ID: WP_006249781.1
Location: 222190..222879 (690 bp)
Type: Others
Protein ID: WP_006253589.1
Type: Others
Protein ID: WP_006253589.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QH638_RS01175 | 213613..214515 | - | 903 | WP_006249771.1 | DMT family transporter | - |
QH638_RS01180 | 214512..214868 | - | 357 | WP_006249772.1 | dihydroneopterin aldolase | - |
QH638_RS01185 | 214938..215543 | + | 606 | WP_006249773.1 | glycerol-3-phosphate 1-O-acyltransferase PlsY | - |
QH638_RS01190 | 215617..217524 | - | 1908 | WP_006249774.1 | DNA topoisomerase IV subunit B | - |
QH638_RS01195 | 217732..217956 | + | 225 | WP_006249776.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
QH638_RS01200 | 217999..218328 | + | 330 | WP_006249777.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
QH638_RS01205 | 218367..218753 | - | 387 | WP_006249778.1 | Cu(I)-responsive transcriptional regulator | - |
QH638_RS01210 | 218842..219042 | + | 201 | WP_006249779.1 | heavy metal-associated domain-containing protein | - |
QH638_RS01215 | 219095..221287 | + | 2193 | WP_006249780.1 | copper-translocating P-type ATPase | - |
QH638_RS01220 | 221340..222125 | - | 786 | WP_006249781.1 | tRNA pseudouridine(38-40) synthase TruA | - |
QH638_RS01225 | 222190..222879 | - | 690 | WP_006253589.1 | GTP cyclohydrolase I FolE | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A547EKP0 |