Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2411211..2411847 Replicon chromosome
Accession NZ_CP123957
Organism Pseudomonas marginalis strain MGMM3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QGQ83_RS11065 Protein ID WP_115487095.1
Coordinates 2411443..2411847 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QGQ83_RS11060 Protein ID WP_115487096.1
Coordinates 2411211..2411450 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QGQ83_RS11040 (QGQ83_11040) 2406530..2407294 - 765 WP_281113999.1 amino acid ABC transporter ATP-binding protein -
QGQ83_RS11045 (QGQ83_11045) 2407319..2408197 - 879 WP_025859372.1 amino acid ABC transporter permease -
QGQ83_RS11050 (QGQ83_11050) 2408304..2409731 - 1428 WP_281114000.1 argininosuccinate lyase -
QGQ83_RS11055 (QGQ83_11055) 2409925..2410884 + 960 WP_281114001.1 LysR family transcriptional regulator -
QGQ83_RS11060 (QGQ83_11060) 2411211..2411450 + 240 WP_115487096.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QGQ83_RS11065 (QGQ83_11065) 2411443..2411847 + 405 WP_115487095.1 type II toxin-antitoxin system VapC family toxin Toxin
QGQ83_RS11070 (QGQ83_11070) 2411878..2412525 - 648 WP_057704184.1 HAD-IB family hydrolase -
QGQ83_RS11075 (QGQ83_11075) 2412599..2413312 - 714 WP_281114002.1 HNH endonuclease -
QGQ83_RS11080 (QGQ83_11080) 2413509..2414759 - 1251 WP_024077017.1 ribonucleotide-diphosphate reductase subunit beta -
QGQ83_RS11085 (QGQ83_11085) 2415270..2415539 - 270 WP_027607759.1 DUF2790 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15044.37 Da        Isoelectric Point: 7.3571

>T279256 WP_115487095.1 NZ_CP123957:2411443-2411847 [Pseudomonas marginalis]
MIKYMLDTNIVIYIIKRRPIEILEKFNANVGRMVISSITLAELMHGAEKSQLVEKNTRAVEDFSSRLDVLNYDDKAAFHY
GSIRSDLEKKGTPIGVNDLHIAGHARSAGLVLVTNNECEFKRVNGLIVENWVAA

Download         Length: 405 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8987.88 Da        Isoelectric Point: 4.0941

>AT279256 WP_115487096.1 NZ_CP123957:2411211-2411450 [Pseudomonas marginalis]
MSSGTIFTNNRTQNIRIPADMRFPAGVKTVEVRAVGRELIISPVENTWDSFFLAGESVSDDFMEERADQTQQERESFDD

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References