Detailed information of TA system TA279221

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-RelB
• Location: 799063..799586
• Replicon: chromosome
• Accession: NZ_CP123912
• Organism: Acinetobacter bereziniae strain UCO-553

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: QHG52_RS03735
• Protein ID: WP_200150101.1
• Coordinates: 799320..799586 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: QHG52_RS03730
• Protein ID: WP_200150100.1
• Coordinates: 799063..799320 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QHG52_RS03710	794439..795455	-	1017	WP_005030968.1	hypothetical protein	-
QHG52_RS03715	795574..796629	-	1056	WP_034715030.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
QHG52_RS03725	797090..798460	+	1371	WP_200150099.1	integrase arm-type DNA-binding domain-containing protein	-
QHG52_RS03730	799063..799320	+	258	WP_200150100.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
QHG52_RS03735	799320..799586	+	267	WP_200150101.1	Txe/YoeB family addiction module toxin	Toxin
QHG52_RS03740	799601..800320	+	720	WP_200150102.1	hypothetical protein	-
QHG52_RS03745	800445..800681	+	237	WP_200150103.1	transcriptional regulator	-
QHG52_RS03750	800697..801011	+	315	WP_200150104.1	AlpA family phage regulatory protein	-
QHG52_RS03755	801014..801658	+	645	WP_200150105.1	hypothetical protein	-
QHG52_RS03760	801658..801966	+	309	WP_200150106.1	hypothetical protein	-
QHG52_RS03765	801969..802238	+	270	WP_200150107.1	hypothetical protein	-
QHG52_RS03770	802239..802586	+	348	WP_200150108.1	CHC2 zinc finger domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (7-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10379.92 Da
• Isoelectric Point: 7.1301

>T279221 WP_200150101.1 NZ_CP123912:799320-799586 [Acinetobacter bereziniae]
MSLSIVFVPDAWDDYVYWQGQDKKTLKRINVLIQAMCRTPFEGIGKPEPLKENLTGYWSRRIADDHRLVYRVTDTEIVII
ACRYHYGD

Nucleotide

• Length: 267 bp

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9463.64 Da
• Isoelectric Point: 5.0859

>AT279221 WP_200150100.1 NZ_CP123912:799063-799320 [Acinetobacter bereziniae]
MKITTATEARANFKTVLDQTIDDADITIIHRRDGENAVLMSESQYNSIMETLHLLSTPANARALERAIAQDKANHGVKRE
LLDAE

Nucleotide

• Length: 258 bp