279219

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5819667..5820295 Replicon chromosome
Accession NZ_CP123909
Organism Pseudomonas atacamensis strain MGMM4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QG303_RS26275 Protein ID WP_016772140.1
Coordinates 5819897..5820295 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID V8RDT4
Locus tag QG303_RS26270 Protein ID WP_024011210.1
Coordinates 5819667..5819897 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QG303_RS26245 (QG303_26245) 5815875..5816219 + 345 WP_024011214.1 hypothetical protein -
QG303_RS26250 (QG303_26250) 5816499..5817557 + 1059 WP_281120532.1 PDDEXK nuclease domain-containing protein -
QG303_RS26255 (QG303_26255) 5817625..5818599 + 975 WP_281120533.1 alpha/beta fold hydrolase -
QG303_RS26260 (QG303_26260) 5818629..5819042 + 414 WP_125925799.1 hypothetical protein -
QG303_RS26265 (QG303_26265) 5819049..5819501 + 453 WP_281120534.1 hypothetical protein -
QG303_RS26270 (QG303_26270) 5819667..5819897 + 231 WP_024011210.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QG303_RS26275 (QG303_26275) 5819897..5820295 + 399 WP_016772140.1 tRNA(fMet)-specific endonuclease VapC Toxin
QG303_RS26280 (QG303_26280) 5820374..5821765 - 1392 WP_016772141.1 GABA permease -
QG303_RS26285 (QG303_26285) 5822309..5823082 + 774 WP_024011209.1 ABC transporter ATP-binding protein -
QG303_RS26290 (QG303_26290) 5823096..5823848 + 753 WP_130900469.1 ABC transporter substrate-binding protein -
QG303_RS26295 (QG303_26295) 5823926..5824621 + 696 WP_281120535.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14547.92 Da        Isoelectric Point: 7.1340

>T279219 WP_016772140.1 NZ_CP123909:5819897-5820295 [Pseudomonas atacamensis]
MIKYMLDTNICIFTIKNKPQIVREAFNRHSGQLCISAITLMELIYGAEKSAAPEKNLAIVEGFVARLDVLPFDNDAAAQA
GMVRSELAKAGTPIGPYDQMIAGHARSLGLIVVTNNVREFQRVSGLRIEDWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8588.62 Da        Isoelectric Point: 4.5203

>AT279219 WP_024011210.1 NZ_CP123909:5819667-5819897 [Pseudomonas atacamensis]
MEQTTIFMSNRSQAVRLPKAVAMPGDVKRVEVIAIGRTRVITPAGESWDSWFDGDSVSPDFMANREQPTEQERESF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V8RDT4

References