279218

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 5669756..5670387 Replicon chromosome
Accession NZ_CP123909
Organism Pseudomonas atacamensis strain MGMM4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QG303_RS25605 Protein ID WP_122881224.1
Coordinates 5669756..5670118 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID J2YH56
Locus tag QG303_RS25610 Protein ID WP_008077592.1
Coordinates 5670118..5670387 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QG303_RS25595 (QG303_25595) 5664885..5668238 + 3354 WP_281120500.1 mechanosensitive channel MscK -
QG303_RS25600 (QG303_25600) 5668287..5669750 + 1464 WP_281120501.1 YdiU family protein -
QG303_RS25605 (QG303_25605) 5669756..5670118 - 363 WP_122881224.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QG303_RS25610 (QG303_25610) 5670118..5670387 - 270 WP_008077592.1 hypothetical protein Antitoxin
QG303_RS25615 (QG303_25615) 5670623..5671057 + 435 WP_258710888.1 thioredoxin TrxC -
QG303_RS25620 (QG303_25620) 5671187..5671957 - 771 WP_024011296.1 ParA family protein -
QG303_RS25625 (QG303_25625) 5672314..5673039 + 726 WP_016772023.1 beta-ketoacyl synthase chain length factor -
QG303_RS25630 (QG303_25630) 5673015..5673827 + 813 WP_281120502.1 lysophospholipid acyltransferase family protein -
QG303_RS25635 (QG303_25635) 5673805..5674080 + 276 WP_125925743.1 phosphopantetheine-binding protein -
QG303_RS25640 (QG303_25640) 5674090..5674344 + 255 WP_016772026.1 acyl carrier protein -
QG303_RS25645 (QG303_25645) 5674341..5674886 + 546 WP_281120503.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13307.21 Da        Isoelectric Point: 7.1674

>T279218 WP_122881224.1 NZ_CP123909:c5670118-5669756 [Pseudomonas atacamensis]
MVRRQPPQRGDVYWIDPNPVAGREMMNRHRFVVITPREINALGVSMTVPVTGGGNFSRNMGLAVAITGHETNGVAVCNQV
RSFDIEQRVRDGTAKFIERLDDVTMSDIVDRVISAIDPLS

Download         Length: 363 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9521.94 Da        Isoelectric Point: 5.1069

>AT279218 WP_008077592.1 NZ_CP123909:c5670387-5670118 [Pseudomonas atacamensis]
MSVTSKIRRQGGAAVITIPPTLLKLLHLEVGAQLELNVVDGELIARPAVAATRKRYSLSELLEGAEELQKLNAQTSETLE
GDSVGRELG

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J2YH56

References