Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 4415666..4416264 | Replicon | chromosome |
Accession | NZ_CP123909 | ||
Organism | Pseudomonas atacamensis strain MGMM4 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | QG303_RS20060 | Protein ID | WP_130901293.1 |
Coordinates | 4416070..4416264 (-) | Length | 65 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | QG303_RS20055 | Protein ID | WP_130901292.1 |
Coordinates | 4415666..4416070 (-) | Length | 135 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QG303_RS20035 (QG303_20035) | 4411268..4412182 | + | 915 | WP_281119865.1 | urea transporter | - |
QG303_RS20040 (QG303_20040) | 4412204..4413028 | + | 825 | WP_039763624.1 | ion transporter | - |
QG303_RS20045 (QG303_20045) | 4413133..4414131 | + | 999 | WP_110601117.1 | sulfate ABC transporter substrate-binding protein | - |
QG303_RS20050 (QG303_20050) | 4414298..4415485 | + | 1188 | WP_024012134.1 | MFS transporter | - |
QG303_RS20055 (QG303_20055) | 4415666..4416070 | - | 405 | WP_130901292.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
QG303_RS20060 (QG303_20060) | 4416070..4416264 | - | 195 | WP_130901293.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
QG303_RS20065 (QG303_20065) | 4416466..4416933 | + | 468 | WP_160768170.1 | helix-turn-helix domain-containing protein | - |
QG303_RS20070 (QG303_20070) | 4416930..4417505 | + | 576 | WP_076566634.1 | PIN domain-containing protein | - |
QG303_RS20075 (QG303_20075) | 4417551..4417955 | - | 405 | WP_016771039.1 | hypothetical protein | - |
QG303_RS20080 (QG303_20080) | 4417981..4419180 | - | 1200 | WP_281119869.1 | c-type cytochrome biogenesis protein CcmI | - |
QG303_RS20085 (QG303_20085) | 4419177..4419647 | - | 471 | WP_016771041.1 | cytochrome c-type biogenesis protein CcmH | - |
QG303_RS20090 (QG303_20090) | 4419644..4420180 | - | 537 | WP_016771042.1 | DsbE family thiol:disulfide interchange protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7249.25 Da Isoelectric Point: 10.2204
>T279215 WP_130901293.1 NZ_CP123909:c4416264-4416070 [Pseudomonas atacamensis]
MKELEEAGWSLDRVAGSHYIFTHRYNPNTIAVPHPKKDLPLGTVKSIRRRAGLFSPPTRHEGDP
MKELEEAGWSLDRVAGSHYIFTHRYNPNTIAVPHPKKDLPLGTVKSIRRRAGLFSPPTRHEGDP
Download Length: 195 bp
Antitoxin
Download Length: 135 a.a. Molecular weight: 14804.86 Da Isoelectric Point: 4.5789
>AT279215 WP_130901292.1 NZ_CP123909:c4416070-4415666 [Pseudomonas atacamensis]
MQYPICIEWGDENTAIGIQIPDIPGAVTVGDSFEEAYNAAVEVAHLMLQEIAAAGQAIPMPTSAAAHRNHPDFAEMGWGM
LELDISPYLGKTEKVNVTLPGYVIQRIDRYVREHNVKSRSSFLADAAMEKLVRY
MQYPICIEWGDENTAIGIQIPDIPGAVTVGDSFEEAYNAAVEVAHLMLQEIAAAGQAIPMPTSAAAHRNHPDFAEMGWGM
LELDISPYLGKTEKVNVTLPGYVIQRIDRYVREHNVKSRSSFLADAAMEKLVRY
Download Length: 405 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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