Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3925916..3926366 Replicon chromosome
Accession NZ_CP123909
Organism Pseudomonas atacamensis strain MGMM4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QG303_RS17780 Protein ID WP_081489880.1
Coordinates 3925916..3926185 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A341FF08
Locus tag QG303_RS17785 Protein ID WP_038862015.1
Coordinates 3926175..3926366 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QG303_RS17760 (QG303_17760) 3921503..3922126 + 624 WP_016774080.1 isochorismate family cysteine hydrolase YcaC -
QG303_RS17765 (QG303_17765) 3922170..3923597 - 1428 WP_073474277.1 mechanosensitive ion channel family protein -
QG303_RS17770 (QG303_17770) 3923706..3924728 - 1023 WP_281119693.1 alpha/beta hydrolase -
QG303_RS17775 (QG303_17775) 3924944..3925843 + 900 WP_024012435.1 LysR family transcriptional regulator -
QG303_RS17780 (QG303_17780) 3925916..3926185 - 270 WP_081489880.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
QG303_RS17785 (QG303_17785) 3926175..3926366 - 192 WP_038862015.1 hypothetical protein Antitoxin
QG303_RS17790 (QG303_17790) 3926675..3927472 + 798 WP_281119694.1 class I SAM-dependent methyltransferase -
QG303_RS17795 (QG303_17795) 3927589..3927897 - 309 WP_281119695.1 putative addiction module antidote protein -
QG303_RS17800 (QG303_17800) 3928210..3928902 - 693 WP_281119696.1 N-acetyltransferase -
QG303_RS17805 (QG303_17805) 3928899..3930089 - 1191 WP_281119697.1 GNAT family N-acetyltransferase -
QG303_RS17810 (QG303_17810) 3930094..3930783 - 690 WP_024012442.1 GNAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10249.64 Da        Isoelectric Point: 7.3990

>T279214 WP_081489880.1 NZ_CP123909:c3926185-3925916 [Pseudomonas atacamensis]
MQIEWRPEAKADLSNILRYIGERNFAAAVSLSKSIEESTTSLSVHPHLYRKGRSPGTREIVVHPNYVVIYEVTDRVEILS
VLHTRQEYP

Download         Length: 270 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7132.82 Da        Isoelectric Point: 4.5698

>AT279214 WP_038862015.1 NZ_CP123909:c3926366-3926175 [Pseudomonas atacamensis]
MDGKIFPDDSGFENDEQAASHDRWLRAKVQASRDDPHPSLPHEDVMADMHALIESMRKKADAD

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A341FF08

References