Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 1917534..1919158 | Replicon | chromosome |
Accession | NZ_CP123909 | ||
Organism | Pseudomonas atacamensis strain MGMM4 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | QG303_RS08920 | Protein ID | WP_281121088.1 |
Coordinates | 1917809..1919158 (-) | Length | 450 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | A0A6I0CP94 |
Locus tag | QG303_RS08915 | Protein ID | WP_071171374.1 |
Coordinates | 1917534..1917812 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QG303_RS08885 (QG303_08885) | 1912975..1913598 | + | 624 | WP_281121085.1 | FMN-binding negative transcriptional regulator | - |
QG303_RS08890 (QG303_08890) | 1913609..1914055 | + | 447 | WP_024014846.1 | GNAT family N-acetyltransferase | - |
QG303_RS08895 (QG303_08895) | 1914068..1914739 | + | 672 | WP_071171378.1 | GNAT family protein | - |
QG303_RS08900 (QG303_08900) | 1914860..1915762 | - | 903 | WP_281121086.1 | homocysteine S-methyltransferase family protein | - |
QG303_RS08905 (QG303_08905) | 1915893..1916693 | + | 801 | WP_281121496.1 | ABC transporter substrate-binding protein | - |
QG303_RS08910 (QG303_08910) | 1916690..1917526 | + | 837 | WP_281121087.1 | amino acid ABC transporter permease | - |
QG303_RS08915 (QG303_08915) | 1917534..1917812 | - | 279 | WP_071171374.1 | helix-turn-helix transcriptional regulator | Antitoxin |
QG303_RS08920 (QG303_08920) | 1917809..1919158 | - | 1350 | WP_281121088.1 | HipA domain-containing protein | Toxin |
QG303_RS08925 (QG303_08925) | 1919527..1921764 | + | 2238 | WP_281121498.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
QG303_RS08930 (QG303_08930) | 1921975..1923783 | - | 1809 | WP_258710755.1 | sodium-extruding oxaloacetate decarboxylase subunit alpha | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 450 a.a. Molecular weight: 49825.36 Da Isoelectric Point: 5.0690
>T279211 WP_281121088.1 NZ_CP123909:c1919158-1917809 [Pseudomonas atacamensis]
MYNLTIQIFTAGQWHDAMILDFDDPEKGFESRCSFGYEADYLVENIEFIGSPFSQAVSALYPLDWEGRRAKTPAFVHDIA
PAGAAKRFLLARLGQERPAEISADLFLLGRSTPAPIGNMRIKESAEAVDERKPIGFKREEVIGRDNRFLEYAYELGAAIG
GATGAGGEAPKLLLAENSAGLLYPDAVLDDEEVRQHWFVKFARNRGGQTDQDILRSEFHYYKALQTLGIETVAAEGLALE
EANKPSLWMRRFDRQVKDGAVSRFAVESIYSLAEVTTPGSAMNHLDVIRMLAGLWRKAGQASQIAGLVADYLRRDLINKI
LGNSDNHGRNTAIIRQENAFQLAPIYDLAPMVMDDEGVTRTTKWPRELERAGDVDWRGVCRVLADSADPHDSLAGLDASA
LFEGLRADARRLAALPDILAASGLPARTMNHPSVHLKNLEQRLKEWDLQ
MYNLTIQIFTAGQWHDAMILDFDDPEKGFESRCSFGYEADYLVENIEFIGSPFSQAVSALYPLDWEGRRAKTPAFVHDIA
PAGAAKRFLLARLGQERPAEISADLFLLGRSTPAPIGNMRIKESAEAVDERKPIGFKREEVIGRDNRFLEYAYELGAAIG
GATGAGGEAPKLLLAENSAGLLYPDAVLDDEEVRQHWFVKFARNRGGQTDQDILRSEFHYYKALQTLGIETVAAEGLALE
EANKPSLWMRRFDRQVKDGAVSRFAVESIYSLAEVTTPGSAMNHLDVIRMLAGLWRKAGQASQIAGLVADYLRRDLINKI
LGNSDNHGRNTAIIRQENAFQLAPIYDLAPMVMDDEGVTRTTKWPRELERAGDVDWRGVCRVLADSADPHDSLAGLDASA
LFEGLRADARRLAALPDILAASGLPARTMNHPSVHLKNLEQRLKEWDLQ
Download Length: 1350 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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