Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB-HicA
Location 5475193..5475632 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QC632_RS24275 Protein ID WP_168028614.1
Coordinates 5475193..5475420 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QC632_RS24280 Protein ID WP_168028616.1
Coordinates 5475423..5475632 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS24250 (QC632_24250) 5470398..5470604 - 207 WP_281023424.1 type II toxin-antitoxin system RelE/ParE family toxin -
QC632_RS24255 (QC632_24255) 5470800..5471678 - 879 WP_281021820.1 inositol monophosphatase family protein -
QC632_RS24260 (QC632_24260) 5471603..5472637 - 1035 WP_281021821.1 phosphotransferase -
QC632_RS24265 (QC632_24265) 5472721..5473770 + 1050 WP_281021822.1 low specificity L-threonine aldolase -
QC632_RS24270 (QC632_24270) 5474446..5474673 - 228 WP_071160799.1 addiction module protein -
QC632_RS24275 (QC632_24275) 5475193..5475420 - 228 WP_168028614.1 type II toxin-antitoxin system HicA family toxin Toxin
QC632_RS24280 (QC632_24280) 5475423..5475632 - 210 WP_168028616.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QC632_RS24285 (QC632_24285) 5476212..5476577 - 366 WP_168028618.1 hypothetical protein -
QC632_RS24290 (QC632_24290) 5478306..5479895 - 1590 WP_281021823.1 apolipoprotein N-acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(10-65)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8538.97 Da        Isoelectric Point: 10.0127

>T279206 WP_168028614.1 NZ_CP123897:c5475420-5475193 [Methylomonas sp. UP202]
MGNLPVLKPREIIALLEILGFTETRQRGSHKQFRHPDGRCTTVPFHAGRDISPILLRQIAKDIGLTVEEFLKYQA

Download         Length: 228 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7669.68 Da        Isoelectric Point: 3.9484

>AT279206 WP_168028616.1 NZ_CP123897:c5475632-5475423 [Methylomonas sp. UP202]
MRVYTAIIERCRDTGLYVGFIPGFTGAHSQAESLDELNQNLREVIEMLLEDGEPILEAEFVGTQNVVVA

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References