Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 5451781..5452346 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QC632_RS24145 Protein ID WP_281021804.1
Coordinates 5451781..5452122 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QC632_RS24150 Protein ID WP_281021805.1
Coordinates 5452119..5452346 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS24115 (QC632_24115) 5447246..5447806 + 561 WP_281021798.1 Uma2 family endonuclease -
QC632_RS24120 (QC632_24120) 5447919..5448290 + 372 WP_281021799.1 DUF1640 domain-containing protein -
QC632_RS24125 (QC632_24125) 5448385..5448837 + 453 WP_281021800.1 TerB family tellurite resistance protein -
QC632_RS24130 (QC632_24130) 5448875..5449231 + 357 WP_281021801.1 hypothetical protein -
QC632_RS24135 (QC632_24135) 5449590..5450420 - 831 WP_281021802.1 VPLPA-CTERM sorting domain-containing protein -
QC632_RS24140 (QC632_24140) 5450513..5451127 - 615 WP_281021803.1 PEP-CTERM sorting domain-containing protein -
QC632_RS24145 (QC632_24145) 5451781..5452122 - 342 WP_281021804.1 DUF5615 family PIN-like protein Toxin
QC632_RS24150 (QC632_24150) 5452119..5452346 - 228 WP_281021805.1 DUF433 domain-containing protein Antitoxin
QC632_RS24155 (QC632_24155) 5452966..5455131 - 2166 WP_281021806.1 zeta toxin family protein -
QC632_RS24160 (QC632_24160) 5455311..5456129 - 819 WP_281021807.1 hypothetical protein -
QC632_RS24165 (QC632_24165) 5456703..5456792 - 90 Protein_4772 twin-arginine translocase TatA/TatE family subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(9-64)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13063.09 Da        Isoelectric Point: 4.6286

>T279205 WP_281021804.1 NZ_CP123897:c5452122-5451781 [Methylomonas sp. UP202]
MIFWVDAQLPPNLADWLRWTFKVEAYALRELGLRDANDLEIFERARQEGIVLISKDSDFVELILRQKPPPQLLWVTCGNT
TNQRLQALFNQVFPQALQLLAEGHMVVELADKS

Download         Length: 342 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8422.82 Da        Isoelectric Point: 4.9856

>AT279205 WP_281021805.1 NZ_CP123897:c5452346-5452119 [Methylomonas sp. UP202]
MNEQVESRITHNPLQCGGKPCIRGMRIRVSDILQMLAEGVSNEIILLDYPDLELADIQACLLYAARRANLERLVA

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References