Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3347297..3347835 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QC632_RS14955 Protein ID WP_281020611.1
Coordinates 3347539..3347835 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QC632_RS14950 Protein ID WP_281020610.1
Coordinates 3347297..3347542 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS14935 (QC632_14935) 3344364..3345206 - 843 WP_281020608.1 hypothetical protein -
QC632_RS14940 (QC632_14940) 3345312..3346091 - 780 WP_281020609.1 VPLPA-CTERM sorting domain-containing protein -
QC632_RS14945 (QC632_14945) 3346578..3347135 + 558 WP_071158132.1 hypothetical protein -
QC632_RS14950 (QC632_14950) 3347297..3347542 + 246 WP_281020610.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QC632_RS14955 (QC632_14955) 3347539..3347835 + 297 WP_281020611.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC632_RS14960 (QC632_14960) 3348021..3349730 + 1710 WP_281020612.1 hypothetical protein -
QC632_RS14965 (QC632_14965) 3349872..3350216 - 345 WP_281020613.1 hypothetical protein -
QC632_RS14970 (QC632_14970) 3350323..3351693 - 1371 WP_281020614.1 DUF6519 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11585.25 Da        Isoelectric Point: 6.8684

>T279200 WP_281020611.1 NZ_CP123897:3347539-3347835 [Methylomonas sp. UP202]
MKPSYRIRQLAAEDLEHIWLYTFQQWGPEQADRYLRALFDRFTWLAEYPKLGKARDDIKPGYFCFPEGRHLVFYIATNTG
IEIIGVPHQNMDVINHVG

Download         Length: 297 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9318.51 Da        Isoelectric Point: 6.4694

>AT279200 WP_281020610.1 NZ_CP123897:3347297-3347542 [Methylomonas sp. UP202]
MARNTSVTLGDHFDNFVQEKIQQGRFLSVSEAVRAGLRKLEEEELKLQTLRAKLQAGEDSPLQENFDQEQFLASMRKKHS
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References