Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1010746..1011254 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QC632_RS04515 Protein ID WP_281022372.1
Coordinates 1010994..1011254 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QC632_RS04510 Protein ID WP_281022371.1
Coordinates 1010746..1010997 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS04480 (QC632_04480) 1005905..1006216 - 312 WP_281020173.1 IS66 family insertion sequence element accessory protein TnpB -
QC632_RS04485 (QC632_04485) 1006986..1007342 + 357 WP_168032017.1 hypothetical protein -
QC632_RS04490 (QC632_04490) 1007428..1007994 + 567 WP_168032015.1 hypothetical protein -
QC632_RS04495 (QC632_04495) 1008088..1009869 - 1782 WP_281022369.1 urease subunit alpha -
QC632_RS04500 (QC632_04500) 1009866..1010183 - 318 WP_281022370.1 urease subunit beta -
QC632_RS04505 (QC632_04505) 1010311..1010613 - 303 WP_054761860.1 urease subunit gamma -
QC632_RS04510 (QC632_04510) 1010746..1010997 + 252 WP_281022371.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QC632_RS04515 (QC632_04515) 1010994..1011254 + 261 WP_281022372.1 Txe/YoeB family addiction module toxin Toxin
QC632_RS04520 (QC632_04520) 1011610..1012140 - 531 WP_281022373.1 transposase -
QC632_RS04525 (QC632_04525) 1012195..1012761 - 567 WP_168032007.1 hypothetical protein -
QC632_RS04530 (QC632_04530) 1013321..1014166 - 846 WP_281022374.1 urease accessory protein UreD -
QC632_RS04535 (QC632_04535) 1014259..1014570 - 312 WP_281022375.1 GIY-YIG nuclease family protein -
QC632_RS04540 (QC632_04540) 1014828..1015601 - 774 WP_281023366.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10270.73 Da        Isoelectric Point: 9.6408

>T279194 WP_281022372.1 NZ_CP123897:1010994-1011254 [Methylomonas sp. UP202]
VKITFSSDAWDSYLYWQTTDKAILKRINQLIKEIQRQPFEGIGKPEPLKHGLSGYWSRRINDEHRIVYKVSGDTLLIAQL
RFHYEY

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9144.35 Da        Isoelectric Point: 4.4488

>AT279194 WP_281022371.1 NZ_CP123897:1010746-1010997 [Methylomonas sp. UP202]
MDAISYSAARANLAKTMDKVCADHAPIIITRKSESPVVMLSLEDYQAMEETAYLLRSPANARRLLESIAELESGQGTERD
LSE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References