Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 619585..620224 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QC632_RS02770 Protein ID WP_281022158.1
Coordinates 619823..620224 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QC632_RS02765 Protein ID WP_281022157.1
Coordinates 619585..619818 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS02755 (QC632_02755) 615030..616142 - 1113 WP_281022155.1 ribonucleotide-diphosphate reductase subunit beta -
QC632_RS02760 (QC632_02760) 616139..619018 - 2880 WP_281022156.1 ribonucleoside-diphosphate reductase subunit alpha -
QC632_RS02765 (QC632_02765) 619585..619818 + 234 WP_281022157.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QC632_RS02770 (QC632_02770) 619823..620224 + 402 WP_281022158.1 type II toxin-antitoxin system VapC family toxin Toxin
QC632_RS02775 (QC632_02775) 620926..621192 + 267 WP_071154930.1 DUF2281 domain-containing protein -
QC632_RS02780 (QC632_02780) 621192..621575 + 384 WP_281022159.1 type II toxin-antitoxin system VapC family toxin -
QC632_RS02785 (QC632_02785) 622514..623440 + 927 WP_281022160.1 hypothetical protein -
QC632_RS02790 (QC632_02790) 623437..624024 + 588 WP_281022161.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15010.41 Da        Isoelectric Point: 7.5181

>T279191 WP_281022158.1 NZ_CP123897:619823-620224 [Methylomonas sp. UP202]
MLKYLLDTNIVIYVIKRRPIEVLATFNRHHGRMAISAVTLAELIHGAEKSQFPERNLATVEDFCSRLQVLPYNDSAAMHY
GGIRAALEKIGQPIGVNDLHIAAHARSHGLILVSNNLREFERVPGLLMENWLE

Download         Length: 402 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8636.57 Da        Isoelectric Point: 4.4883

>AT279191 WP_281022157.1 NZ_CP123897:619585-619818 [Methylomonas sp. UP202]
MTTSTVFTNNRSQAVRLPADMRFPDSVKKVEVRAVGQERMIAPADAAWDSFFLDGPSVSDDFLNERPGQQQGERESF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References