Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2256927..2257580 Replicon chromosome
Accession NZ_CP123854
Organism Acinetobacter baumannii strain WB4

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QG728_RS10885 Protein ID WP_025467596.1
Coordinates 2257191..2257580 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag QG728_RS10880 Protein ID WP_001288210.1
Coordinates 2256927..2257184 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QG728_RS10860 (QG728_10860) 2252450..2253457 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
QG728_RS10865 (QG728_10865) 2253476..2253853 + 378 WP_001216380.1 50S ribosomal protein L17 -
QG728_RS10870 (QG728_10870) 2254028..2255518 + 1491 WP_000415138.1 NAD(P)/FAD-dependent oxidoreductase -
QG728_RS10875 (QG728_10875) 2255567..2256739 - 1173 WP_262094012.1 acyl-CoA dehydrogenase family protein -
QG728_RS10880 (QG728_10880) 2256927..2257184 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
QG728_RS10885 (QG728_10885) 2257191..2257580 + 390 WP_025467596.1 membrane protein Toxin
QG728_RS10890 (QG728_10890) 2258350..2259435 + 1086 WP_000049106.1 hypothetical protein -
QG728_RS10895 (QG728_10895) 2259513..2260079 + 567 WP_000651536.1 rhombosortase -
QG728_RS10900 (QG728_10900) 2260267..2262462 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T279190 WP_025467596.1 NZ_CP123854:2257191-2257580 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT279190 WP_001288210.1 NZ_CP123854:2256927-2257184 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References