Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 348723..349393 Replicon plasmid pAtH25_79a
Accession NZ_CP123849
Organism Agrobacterium fabacearum strain H25/79

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6L82_RS24610 Protein ID WP_003517201.1
Coordinates 348974..349393 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A7U5CZ71
Locus tag G6L82_RS24605 Protein ID WP_038496682.1
Coordinates 348723..348977 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L82_RS24595 (G6L82_024595) 346193..347200 + 1008 WP_173995352.1 sensor histidine kinase -
G6L82_RS24600 (G6L82_024600) 347734..348339 - 606 WP_065662894.1 J domain-containing protein -
G6L82_RS24605 (G6L82_024605) 348723..348977 + 255 WP_038496682.1 plasmid stabilization protein Antitoxin
G6L82_RS24610 (G6L82_024610) 348974..349393 + 420 WP_003517201.1 type II toxin-antitoxin system VapC family toxin Toxin
G6L82_RS24615 (G6L82_024615) 349613..350509 - 897 WP_013637432.1 dihydrodipicolinate synthase family protein -
G6L82_RS24620 (G6L82_024620) 350542..351423 - 882 WP_145166914.1 SMP-30/gluconolactonase/LRE family protein -
G6L82_RS24625 (G6L82_024625) 351479..352198 - 720 WP_003517195.1 FCD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..628949 628949


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15036.22 Da        Isoelectric Point: 5.1532

>T279166 WP_003517201.1 NZ_CP123849:348974-349393 [Agrobacterium fabacearum]
MILLDTNVISEPWKPVPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARARASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9297.54 Da        Isoelectric Point: 7.3219

>AT279166 WP_038496682.1 NZ_CP123849:348723-348977 [Agrobacterium fabacearum]
MPAVTIRNLSEETHRALRVRAAHHGRSTEAEIRDIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPAKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U5CZ71

References