Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 108101..108648 Replicon plasmid pAtH25_79a
Accession NZ_CP123849
Organism Agrobacterium fabacearum strain H25/79

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L82_RS23395 Protein ID WP_173995409.1
Coordinates 108355..108648 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID F0LFW5
Locus tag G6L82_RS23390 Protein ID WP_013637268.1
Coordinates 108101..108355 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L82_RS23365 (G6L82_023365) 104530..104799 + 270 WP_035201239.1 hypothetical protein -
G6L82_RS23370 (G6L82_023370) 104814..106028 + 1215 WP_173995407.1 low temperature requirement protein A -
G6L82_RS23375 (G6L82_023375) 106041..106613 + 573 WP_051376994.1 DUF924 family protein -
G6L82_RS23380 (G6L82_023380) 106692..107450 + 759 WP_035201237.1 type 1 glutamine amidotransferase domain-containing protein -
G6L82_RS23385 (G6L82_023385) 107543..107893 + 351 WP_173995408.1 hypothetical protein -
G6L82_RS23390 (G6L82_023390) 108101..108355 + 255 WP_013637268.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L82_RS23395 (G6L82_023395) 108355..108648 + 294 WP_173995409.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L82_RS23400 (G6L82_023400) 108786..109628 - 843 WP_236768996.1 hypothetical protein -
G6L82_RS23405 (G6L82_023405) 109625..110881 - 1257 WP_173995411.1 MSMEG_0569 family flavin-dependent oxidoreductase -
G6L82_RS23410 (G6L82_023410) 110893..111171 - 279 WP_013637307.1 MSMEG_0570 family nitrogen starvation response protein -
G6L82_RS23415 (G6L82_023415) 111164..112135 - 972 WP_173995412.1 sll0787 family AIR synthase-like protein -
G6L82_RS23420 (G6L82_023420) 112135..112674 - 540 WP_173995413.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..628949 628949


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11117.71 Da        Isoelectric Point: 5.8932

>T279163 WP_173995409.1 NZ_CP123849:108355-108648 [Agrobacterium fabacearum]
MPFSLSVQAEEDIISIAEEGIRIFGALVARQYHDELFALLELIATNPRMARERHEISPPVRIHPFKAHPVVYRVIEDGSV
FVIRIRHGHEDWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9410.52 Da        Isoelectric Point: 8.5776

>AT279163 WP_013637268.1 NZ_CP123849:108101-108355 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRADIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LFW5

References