279161

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 344252..344714 Replicon chromosome
Accession NZ_CP123847
Organism Agrobacterium fabacearum strain H25/79

Toxin (Protein)


Gene name pasB Uniprot ID A0A9E8LFT7
Locus tag G6L82_RS01600 Protein ID WP_065703878.1
Coordinates 344252..344503 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID F0L6V5
Locus tag G6L82_RS01605 Protein ID WP_013635548.1
Coordinates 344487..344714 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L82_RS01570 (G6L82_001570) 339290..340063 - 774 WP_065658316.1 L,D-transpeptidase -
G6L82_RS01575 (G6L82_001575) 340301..340930 + 630 WP_004432231.1 DNA-3-methyladenine glycosylase I -
G6L82_RS01580 (G6L82_001580) 340927..341370 + 444 WP_013635544.1 hypothetical protein -
G6L82_RS01585 (G6L82_001585) 341386..342429 - 1044 WP_065703874.1 YeiH family protein -
G6L82_RS01590 (G6L82_001590) 342512..343429 + 918 WP_173994927.1 LysR substrate-binding domain-containing protein -
G6L82_RS01595 (G6L82_001595) 343481..344245 - 765 WP_065703876.1 hypothetical protein -
G6L82_RS01600 (G6L82_001600) 344252..344503 - 252 WP_065703878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L82_RS01605 (G6L82_001605) 344487..344714 - 228 WP_013635548.1 DUF6290 family protein Antitoxin
G6L82_RS01610 (G6L82_001610) 344871..346496 + 1626 WP_065703880.1 histidine--tRNA ligase -
G6L82_RS01615 (G6L82_001615) 346501..346869 + 369 WP_026330619.1 VOC family protein -
G6L82_RS01620 (G6L82_001620) 346886..348013 + 1128 WP_004432209.1 ATP phosphoribosyltransferase regulatory subunit -
G6L82_RS01625 (G6L82_001625) 348010..348702 + 693 WP_004432208.1 ATP phosphoribosyltransferase -
G6L82_RS01630 (G6L82_001630) 348766..349212 - 447 WP_065703882.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-82)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9851.38 Da        Isoelectric Point: 9.5687

>T279161 WP_065703878.1 NZ_CP123847:c344503-344252 [Agrobacterium fabacearum]
VIWTIEYDVLVQKEMRKIDPQTRQRIRVAALDNPRQTGAALQGSELGSFWRYRVGDYRIICDIQDHKLVVLVVEIGHRRE
IYR

Download         Length: 252 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8909.92 Da        Isoelectric Point: 4.7254

>AT279161 WP_013635548.1 NZ_CP123847:c344714-344487 [Agrobacterium fabacearum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVVSAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0L6V5

References