Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 454528..455318 Replicon plasmid pAt15-1187-1-2a1
Accession NZ_CP123840
Organism Agrobacterium fabacearum strain 15-1187-1-2a

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag A6U93_RS26095 Protein ID WP_065660620.1
Coordinates 454821..455318 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A8A5PI45
Locus tag A6U93_RS26090 Protein ID WP_035200890.1
Coordinates 454528..454824 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U93_RS26070 (A6U93_26070) 449927..451651 + 1725 WP_065660622.1 ABC transporter ATP-binding protein -
A6U93_RS26075 (A6U93_26075) 451696..452883 + 1188 WP_013637437.1 galactarate dehydratase -
A6U93_RS26080 (A6U93_26080) 452870..453736 + 867 WP_065660621.1 aldose 1-epimerase -
A6U93_RS26085 (A6U93_26085) 453948..454345 + 398 Protein_457 DDE-type integrase/transposase/recombinase -
A6U93_RS26090 (A6U93_26090) 454528..454824 + 297 WP_035200890.1 DUF1778 domain-containing protein Antitoxin
A6U93_RS26095 (A6U93_26095) 454821..455318 + 498 WP_065660620.1 GNAT family N-acetyltransferase Toxin
A6U93_RS26100 (A6U93_26100) 455597..456262 - 666 WP_081308998.1 GNAT family N-acetyltransferase -
A6U93_RS26105 (A6U93_26105) 456228..457388 - 1161 WP_065660619.1 Gfo/Idh/MocA family oxidoreductase -
A6U93_RS26110 (A6U93_26110) 457420..458670 - 1251 WP_065660618.1 ROK family transcriptional regulator -
A6U93_RS26115 (A6U93_26115) 458883..459842 + 960 WP_065660617.1 extracellular solute-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..659230 659230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-142)

Antitoxin

Vibrio phage ICP1, Orf50

(8-97)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17813.43 Da        Isoelectric Point: 6.8629

>T279156 WP_065660620.1 NZ_CP123840:454821-455318 [Agrobacterium fabacearum]
VTLSAPVPLADHHELAEFNSGVPELDDWLRRRARANQAGGASRTFVVCDESRVIAYYALVSGFVKPPEVPGRFRRNMPDP
IPVAVLGRLAIDQSCQGRGIGRALVRDAGLRLLNAAEVLGIRGVLVHAISDDARAFYEAVGFLSSPSDPMMLMVGLHDLN
NALNT

Download         Length: 498 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11053.60 Da        Isoelectric Point: 7.0159

>AT279156 WP_035200890.1 NZ_CP123840:454528-454824 [Agrobacterium fabacearum]
MPTSHTGKSPDASVQLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIVTVSPEIYAEYLARLDAPAQ
PNERLKRTMSTKAPWDEA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References