Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 442032..442702 Replicon plasmid pAt15-1187-1-2a1
Accession NZ_CP123840
Organism Agrobacterium fabacearum strain 15-1187-1-2a

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A6U93_RS26035 Protein ID WP_003517201.1
Coordinates 442283..442702 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F0LGD9
Locus tag A6U93_RS26030 Protein ID WP_003517203.1
Coordinates 442032..442286 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U93_RS26020 (A6U93_26020) 439506..440507 + 1002 WP_003517209.1 sensor histidine kinase -
A6U93_RS26025 (A6U93_26025) 441043..441648 - 606 WP_003517207.1 J domain-containing protein -
A6U93_RS26030 (A6U93_26030) 442032..442286 + 255 WP_003517203.1 plasmid stabilization protein Antitoxin
A6U93_RS26035 (A6U93_26035) 442283..442702 + 420 WP_003517201.1 type II toxin-antitoxin system VapC family toxin Toxin
A6U93_RS26040 (A6U93_26040) 442842..443738 - 897 WP_013637432.1 dihydrodipicolinate synthase family protein -
A6U93_RS26045 (A6U93_26045) 443771..444652 - 882 WP_065660624.1 SMP-30/gluconolactonase/LRE family protein -
A6U93_RS26050 (A6U93_26050) 444709..445428 - 720 WP_003517195.1 FCD domain-containing protein -
A6U93_RS26055 (A6U93_26055) 445728..447677 + 1950 WP_065660623.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..659230 659230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15036.22 Da        Isoelectric Point: 5.1532

>T279155 WP_003517201.1 NZ_CP123840:442283-442702 [Agrobacterium fabacearum]
MILLDTNVISEPWKPVPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARARASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9253.53 Da        Isoelectric Point: 8.9520

>AT279155 WP_003517203.1 NZ_CP123840:442032-442286 [Agrobacterium fabacearum]
MPAVTIRNLSEETHRALRVRAAHHGRSTEAEIRAIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPAKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LGD9

References