Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 166398..166945 Replicon plasmid pAt15-1187-1-2a1
Accession NZ_CP123840
Organism Agrobacterium fabacearum strain 15-1187-1-2a

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag A6U93_RS24625 Protein ID WP_081308828.1
Coordinates 166652..166945 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag A6U93_RS24620 Protein ID WP_065659084.1
Coordinates 166398..166652 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U93_RS24605 (A6U93_24605) 163290..163781 + 492 WP_065659082.1 nitrate reductase cytochrome c-type subunit -
A6U93_RS24610 (A6U93_24610) 163784..164479 + 696 WP_272479405.1 cytochrome c3 family protein -
A6U93_RS24615 (A6U93_24615) 164964..166202 + 1239 WP_065659083.1 Fic family protein -
A6U93_RS24620 (A6U93_24620) 166398..166652 + 255 WP_065659084.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
A6U93_RS24625 (A6U93_24625) 166652..166945 + 294 WP_081308828.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6U93_RS24630 (A6U93_24630) 167020..167253 - 234 WP_065659086.1 hypothetical protein -
A6U93_RS24635 (A6U93_24635) 167723..168445 + 723 WP_158007500.1 UTRA domain-containing protein -
A6U93_RS24640 (A6U93_24640) 168598..169725 + 1128 WP_065659087.1 ABC transporter ATP-binding protein -
A6U93_RS24645 (A6U93_24645) 169715..170359 + 645 WP_065659088.1 ABC transporter permease subunit -
A6U93_RS24650 (A6U93_24650) 170364..171101 + 738 WP_065659089.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..659230 659230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-75)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11157.88 Da        Isoelectric Point: 6.6028

>T279154 WP_081308828.1 NZ_CP123840:166652-166945 [Agrobacterium fabacearum]
MPFSLSVQAEEDIISIAEECIRIFGALVARQYHGELFALLELIATNPRMARERHEISPPVRIHPFKAHLVVYRIIEDGSV
FVIRIRHGHEHWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9512.61 Da        Isoelectric Point: 6.3247

>AT279154 WP_065659084.1 NZ_CP123840:166398-166652 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVETQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRVDIS
RGRD

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References