Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5599589..5601324 Replicon chromosome
Accession NZ_CP123771
Organism Pseudomonas viciae strain YsS1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag QCD61_RS24465 Protein ID WP_280944417.1
Coordinates 5599589..5600233 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag QCD61_RS24470 Protein ID WP_280944418.1
Coordinates 5600230..5601324 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCD61_RS24450 (QCD61_24450) 5595091..5597460 - 2370 WP_280944414.1 DEAD/DEAH box helicase family protein -
QCD61_RS24455 (QCD61_24455) 5597663..5598778 - 1116 WP_280944415.1 endonuclease NucS -
QCD61_RS24460 (QCD61_24460) 5599011..5599592 + 582 WP_280944416.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
QCD61_RS24465 (QCD61_24465) 5599589..5600233 + 645 WP_280944417.1 DUF4433 domain-containing protein Toxin
QCD61_RS24470 (QCD61_24470) 5600230..5601324 + 1095 WP_280944418.1 macro domain-containing protein Antitoxin
QCD61_RS24475 (QCD61_24475) 5601515..5601874 - 360 WP_280944419.1 DUF6124 family protein -
QCD61_RS24480 (QCD61_24480) 5602287..5602862 - 576 WP_280944420.1 hypothetical protein -
QCD61_RS24485 (QCD61_24485) 5603053..5603412 - 360 WP_280944421.1 DUF6124 family protein -
QCD61_RS24490 (QCD61_24490) 5604005..5605279 - 1275 WP_212801514.1 glycoside hydrolase family 68 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5588328..5602862 14534
- inside Genomic island - - 5587665..5603412 15747


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24877.60 Da        Isoelectric Point: 8.4140

>T279149 WP_280944417.1 NZ_CP123771:5599589-5600233 [Pseudomonas viciae]
MIYSRLNPEKALIWRIVHRDNLPWILDNGLHCANSNVQSPQYVNIGNPDLIDKRRTRHVPIAPGGVLADYVPFYFTPFSV
MMKNIHSGRSVQQRSNDEIVILVSSLYRIELMGLPFVYTTAHAYPDWTDYYSDLANLGQIDWSIIQRRDFKREPDDPRKM
ERYQAEALIHNHLPITGLLGIMCYTDAMKKRIEQDVAARGLVLPVYARPGWYFQ

Download         Length: 645 bp

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 40863.76 Da        Isoelectric Point: 5.9506

>AT279149 WP_280944418.1 NZ_CP123771:5600230-5601324 [Pseudomonas viciae]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFTENYRLYSAACKAGEVETGKVHVTAANELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENDVKSVAVPPLGAGNGGLKWPEVREQIVEILSDLDVDVLVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPNTENPLNLQFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAGISDVIWFDEGRKAFLQTYLQTEAKEYTQALERTAELIDGFESPFGMELLATVDWLLSQDGISPTVPAVREA
LKHWDGGAGAAARKSKLFDDQALDIALKRLTSSSFRPEMASCQG

Download         Length: 1095 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References