279145

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 267766..268442 Replicon chromosome
Accession NZ_CP123771
Organism Pseudomonas viciae strain YsS1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QCD61_RS01130 Protein ID WP_135843170.1
Coordinates 267766..267948 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QCD61_RS01135 Protein ID WP_135847931.1
Coordinates 268041..268442 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCD61_RS01115 (QCD61_01115) 263803..265764 + 1962 WP_178084290.1 choline transporter BetT -
QCD61_RS01120 (QCD61_01120) 265888..266628 - 741 WP_135843168.1 SDR family oxidoreductase -
QCD61_RS01125 (QCD61_01125) 266746..267636 + 891 WP_135843169.1 LysR family transcriptional regulator -
QCD61_RS01130 (QCD61_01130) 267766..267948 + 183 WP_135843170.1 type II toxin-antitoxin system HicA family toxin Toxin
QCD61_RS01135 (QCD61_01135) 268041..268442 + 402 WP_135847931.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QCD61_RS01140 (QCD61_01140) 268508..269545 + 1038 WP_135843171.1 L-glyceraldehyde 3-phosphate reductase -
QCD61_RS01145 (QCD61_01145) 269602..270444 - 843 WP_135843172.1 taurine dioxygenase -
QCD61_RS01150 (QCD61_01150) 270495..271334 - 840 WP_256454055.1 taurine ABC transporter permease TauC -
QCD61_RS01155 (QCD61_01155) 271331..272125 - 795 WP_265072583.1 taurine ABC transporter ATP-binding subunit -
QCD61_RS01160 (QCD61_01160) 272151..273128 - 978 WP_135843175.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6871.99 Da        Isoelectric Point: 10.6627

>T279145 WP_135843170.1 NZ_CP123771:267766-267948 [Pseudomonas viciae]
MRSREMIRKIEEDGWYLVAVKGSHHQYKHSFKAGRVTIKHPDADLPKGTINSILKQAGLK

Download         Length: 183 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14625.30 Da        Isoelectric Point: 4.4085

>AT279145 WP_135847931.1 NZ_CP123771:268041-268442 [Pseudomonas viciae]
MKFPVVLHKDADSEYGVTVPDVPGCFSAGSTVGQAFENVKEALSLHYEGLVADGEPLPQIHEIDDHLDNPDYAGGIWGVV
EFDVTPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References