Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 33766..34291 Replicon plasmid pAP8900-2
Accession NZ_CP123767
Organism Acinetobacter pittii strain AP8900

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QFB56_RS20060 Protein ID WP_005130374.1
Coordinates 34004..34291 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QFB56_RS20055 Protein ID WP_005130375.1
Coordinates 33766..34014 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB56_RS20030 (QFB56_20030) 30819..31733 - 915 WP_004843977.1 replication initiation protein RepM -
QFB56_RS20035 (QFB56_20035) 32206..32835 + 630 WP_005130378.1 AAA family ATPase -
QFB56_RS20040 (QFB56_20040) 32832..33071 + 240 WP_005130377.1 hypothetical protein -
QFB56_RS20045 (QFB56_20045) 33187..33255 + 69 Protein_30 helix-turn-helix domain-containing protein -
QFB56_RS20050 (QFB56_20050) 33338..33763 + 426 WP_005130376.1 hypothetical protein -
QFB56_RS20055 (QFB56_20055) 33766..34014 + 249 WP_005130375.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QFB56_RS20060 (QFB56_20060) 34004..34291 + 288 WP_005130374.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QFB56_RS20065 (QFB56_20065) 34452..34601 - 150 WP_079878061.1 DUF4113 domain-containing protein -
QFB56_RS20070 (QFB56_20070) 35094..35660 + 567 WP_000678311.1 recombinase family protein -
QFB56_RS20075 (QFB56_20075) 35882..36496 - 615 WP_081318675.1 hypothetical protein -
QFB56_RS20080 (QFB56_20080) 36605..37084 - 480 WP_139118978.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid msr(E) / mph(E) / tet(39) / cmlB1 / sul2 / aph(3'')-Ib / aph(6)-Id - 1..43600 43600


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11146.00 Da        Isoelectric Point: 10.1961

>T279140 WP_005130374.1 NZ_CP123767:34004-34291 [Acinetobacter pittii]
MTYKLDFLEEALAEWNKLNPSIKQPLKKKLIKVLENPRIPKNKLPGHPNRYKIKLRSVGYRLVYEVIDDEVIFIVIAVGR
RENNAVYDEANSRHS

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9258.77 Da        Isoelectric Point: 5.0491

>AT279140 WP_005130375.1 NZ_CP123767:33766-34014 [Acinetobacter pittii]
MTQLIHARMTASITELKKSPMDTVLAGKGEPVAILNRNIPAFYCVPADLYETMMEQLEDLELNKIADARANQKRIRVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References