Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 489199..489852 Replicon chromosome
Accession NZ_CP123765
Organism Acinetobacter pittii strain AP8900

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QFB56_RS02430 Protein ID WP_032057380.1
Coordinates 489463..489852 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag QFB56_RS02425 Protein ID WP_002117064.1
Coordinates 489199..489456 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB56_RS02405 (QFB56_02405) 484712..485719 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
QFB56_RS02410 (QFB56_02410) 485738..486115 + 378 WP_002049717.1 50S ribosomal protein L17 -
QFB56_RS02415 (QFB56_02415) 486297..487787 + 1491 WP_032057377.1 NAD(P)/FAD-dependent oxidoreductase -
QFB56_RS02420 (QFB56_02420) 487838..489010 - 1173 WP_032057378.1 acyl-CoA dehydrogenase family protein -
QFB56_RS02425 (QFB56_02425) 489199..489456 + 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
QFB56_RS02430 (QFB56_02430) 489463..489852 + 390 WP_032057380.1 hypothetical protein Toxin
QFB56_RS02435 (QFB56_02435) 490623..491711 + 1089 WP_032057381.1 hypothetical protein -
QFB56_RS02440 (QFB56_02440) 491796..492371 + 576 WP_005078319.1 rhombosortase -
QFB56_RS02445 (QFB56_02445) 492551..494761 + 2211 WP_032057383.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15452.56 Da        Isoelectric Point: 7.7627

>T279136 WP_032057380.1 NZ_CP123765:489463-489852 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YCGEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT279136 WP_002117064.1 NZ_CP123765:489199-489456 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References