Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 906740..907394 Replicon chromosome
Accession NZ_CP123759
Organism Arsenophonus apicola strain aApi_AU

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QG404_RS05155 Protein ID WP_180558768.1
Coordinates 906987..907394 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QG404_RS05150 Protein ID WP_026821812.1
Coordinates 906740..907006 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QG404_RS05130 (QG404_05135) 902287..903144 + 858 WP_280939305.1 hypothetical protein -
QG404_RS05135 (QG404_05140) 903238..904074 + 837 WP_280939306.1 hypothetical protein -
QG404_RS05140 (QG404_05145) 904324..904656 + 333 WP_280939307.1 hypothetical protein -
QG404_RS05145 (QG404_05150) 905494..906480 - 987 WP_280939308.1 tRNA-modifying protein YgfZ -
QG404_RS05150 (QG404_05155) 906740..907006 + 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QG404_RS05155 (QG404_05160) 906987..907394 + 408 WP_180558768.1 protein YgfX Toxin
QG404_RS05160 (QG404_05165) 907410..907928 - 519 WP_280939309.1 flavodoxin FldB -
QG404_RS05165 (QG404_05170) 908411..909724 - 1314 WP_280939310.1 S8 family serine peptidase -
QG404_RS05170 (QG404_05175) 911373..912284 + 912 WP_180558772.1 site-specific tyrosine recombinase XerD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279134 WP_180558768.1 NZ_CP123759:906987-907394 [Arsenophonus apicola]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSLVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279134 WP_026821812.1 NZ_CP123759:906740-907006 [Arsenophonus apicola]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References