279132

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) omega-epsilon-zeta/zeta-epsilon
Location 1347065..1347563 Replicon chromosome
Accession NZ_CP123751
Organism Ligilactobacillus animalis strain ZSB1

Toxin (Protein)


Gene name zeta Uniprot ID -
Locus tag QFF56_RS06830 Protein ID WP_283534509.1
Coordinates 1347065..1347289 (-) Length 75 a.a.

Antitoxin (Protein)


Gene name epsilon Uniprot ID Q9AL01
Locus tag QFF56_RS06835 Protein ID WP_002331065.1
Coordinates 1347291..1347563 (-) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFF56_RS06810 (QFF56_06810) 1343894..1344196 - 303 WP_005917836.1 hypothetical protein -
QFF56_RS06815 (QFF56_06815) 1344382..1345026 - 645 WP_283534508.1 Crp/Fnr family transcriptional regulator -
QFF56_RS06820 (QFF56_06820) 1345054..1345977 + 924 WP_016496411.1 IS30 family transposase -
QFF56_RS06825 (QFF56_06825) 1346347..1347027 - 681 WP_001015311.1 IS6-like element IS1216 family transposase -
QFF56_RS06830 (QFF56_06830) 1347065..1347289 - 225 WP_283534509.1 zeta toxin family protein Toxin
QFF56_RS06835 (QFF56_06835) 1347291..1347563 - 273 WP_002331065.1 antitoxin Antitoxin
QFF56_RS06840 (QFF56_06840) 1347580..1347789 - 210 WP_000527318.1 peptide-binding protein -
QFF56_RS06845 (QFF56_06845) 1347888..1348784 - 897 WP_002334978.1 AAA family ATPase -
QFF56_RS06850 (QFF56_06850) 1349103..1349675 - 573 WP_001079938.1 HTH domain-containing protein -
QFF56_RS06855 (QFF56_06855) 1349951..1350745 - 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
QFF56_RS06860 (QFF56_06860) 1350838..1351368 - 531 WP_000627289.1 streptothricin N-acetyltransferase Sat4 -
QFF56_RS06865 (QFF56_06865) 1351365..1352273 - 909 WP_001255866.1 aminoglycoside nucleotidyltransferase ANT(6)-Ia -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element aph(3')-III / ant(6)-Ia / erm(T) - 1340633..1401988 61355
- inside IS/Tn aph(3')-III / ant(6)-Ia - 1346347..1352273 5926


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(27-72)

Antitoxin

(2-90)


Sequences


Toxin        


Download         Length: 75 a.a.        Molecular weight: 8229.40 Da        Isoelectric Point: 8.7488

>T279132 WP_283534509.1 NZ_CP123751:c1347289-1347065 [Ligilactobacillus animalis]
MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSGKTSLRSAIFEETQGNVIVVLLQSFKSTIK

Download         Length: 225 bp


Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10733.17 Da        Isoelectric Point: 4.4865

>AT279132 WP_002331065.1 NZ_CP123751:c1347563-1347291 [Ligilactobacillus animalis]
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVNLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYS
KQILNKEKVA

Download         Length: 273 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A828ZL55

References