279103

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3403455..3404158 Replicon chromosome
Accession NZ_CP123642
Organism Klebsiella pneumoniae strain KpBSB53

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag QFW99_RS17375 Protein ID WP_017880111.1
Coordinates 3403455..3403796 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QFW99_RS17380 Protein ID WP_050131139.1
Coordinates 3403817..3404158 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFW99_RS17345 (3398650) 3398650..3399324 + 675 WP_004186809.1 hypothetical protein -
QFW99_RS17350 (3399326) 3399326..3399673 + 348 WP_004186808.1 hypothetical protein -
QFW99_RS17355 (3399676) 3399676..3400155 + 480 WP_004192264.1 type VI secretion system tube protein TssD -
QFW99_RS17360 (3400348) 3400348..3400686 - 339 Protein_3265 hypothetical protein -
QFW99_RS17365 (3400705) 3400705..3401816 - 1112 Protein_3266 IS3 family transposase -
QFW99_RS17370 (3402184) 3402184..3403191 - 1008 WP_017880110.1 restriction endonuclease -
QFW99_RS17375 (3403455) 3403455..3403796 - 342 WP_017880111.1 TA system toxin CbtA family protein Toxin
QFW99_RS17380 (3403817) 3403817..3404158 - 342 WP_050131139.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QFW99_RS17385 (3404169) 3404169..3404711 - 543 WP_032417798.1 DNA repair protein RadC -
QFW99_RS17390 (3404724) 3404724..3405167 - 444 WP_032417797.1 antirestriction protein -
QFW99_RS17395 (3405198) 3405198..3406019 - 822 WP_032417795.1 DUF932 domain-containing protein -
QFW99_RS17400 (3406140) 3406140..3406613 - 474 WP_031280324.1 hypothetical protein -
QFW99_RS17405 (3406685) 3406685..3407137 - 453 WP_031280325.1 hypothetical protein -
QFW99_RS17410 (3407173) 3407173..3407889 - 717 WP_032417794.1 WYL domain-containing protein -
QFW99_RS17415 (3408133) 3408133..3409008 - 876 WP_017880120.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3399326..3430664 31338


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12811.73 Da        Isoelectric Point: 8.4941

>T279103 WP_017880111.1 NZ_CP123642:c3403796-3403455 [Klebsiella pneumoniae]
MKTLPATNPQAATLYLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
DWQEQSPYLRAVDIMRARQATGLLKRNRISAAR

Download         Length: 342 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12821.45 Da        Isoelectric Point: 6.3148

>AT279103 WP_050131139.1 NZ_CP123642:c3404158-3403817 [Klebsiella pneumoniae]
MKSTDSENDSFLKWGLNCNMTPCFGARLVQEGNRLHYLADRACITGEFSNAESLKLDEVFTRFIRQMESMLTTGEMNPRH
AHSVTLYHNGFTCEADTLGSCGYVYIAVYPTHR

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References