Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 638024..638169 Replicon chromosome
Accession NZ_CP123642
Organism Klebsiella pneumoniae strain KpBSB53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 638060..638162 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 638024..638169 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFW99_RS03625 633154..635214 + 2061 WP_004151449.1 oligopeptidase B -
QFW99_RS03630 635218..635877 - 660 WP_002911407.1 exodeoxyribonuclease X -
QFW99_RS03635 635956..636186 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QFW99_RS03640 636299..636673 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QFW99_RS03645 636677..637546 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
QFW99_RS03650 637563..637901 + 339 WP_002911404.1 YebY family protein -
- 638024..638169 - 146 - - Antitoxin
- 638060..638162 + 103 - - Toxin
QFW99_RS03655 638537..638680 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QFW99_RS03660 638785..639753 - 969 WP_004151446.1 VirK/YbjX family protein -
QFW99_RS03665 639910..640563 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
QFW99_RS03670 640560..640751 - 192 WP_002911395.1 YebW family protein -
QFW99_RS03675 640849..641088 - 240 WP_002911393.1 YebV family protein -
QFW99_RS03680 641204..642637 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T279096 NZ_CP123642:638060-638162 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT279096 NZ_CP123642:c638169-638024 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References