Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PanAT/- |
| Location | 376521..377851 | Replicon | chromosome |
| Accession | NZ_CP123639 | ||
| Organism | Ligilactobacillus faecis strain WILCCON 0062 | ||
Toxin (Protein)
| Gene name | panT | Uniprot ID | - |
| Locus tag | QFX10_RS02065 | Protein ID | WP_280606584.1 |
| Coordinates | 377243..377851 (-) | Length | 203 a.a. |
Antitoxin (Protein)
| Gene name | panA | Uniprot ID | - |
| Locus tag | QFX10_RS02060 | Protein ID | WP_280606583.1 |
| Coordinates | 376521..377240 (-) | Length | 240 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QFX10_RS02055 (QFX10_02055) | 372615..376229 | - | 3615 | WP_280606582.1 | DNA-directed RNA polymerase subunit beta | - |
| QFX10_RS02060 (QFX10_02060) | 376521..377240 | - | 720 | WP_280606583.1 | hypothetical protein | Antitoxin |
| QFX10_RS02065 (QFX10_02065) | 377243..377851 | - | 609 | WP_280606584.1 | hypothetical protein | Toxin |
| QFX10_RS02070 (QFX10_02070) | 377965..378657 | - | 693 | WP_280606585.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| QFX10_RS02075 (QFX10_02075) | 378714..379112 | - | 399 | Protein_372 | DUF697 domain-containing protein | - |
| QFX10_RS02080 (QFX10_02080) | 379328..379873 | + | 546 | WP_280606586.1 | Crp/Fnr family transcriptional regulator | - |
| QFX10_RS02085 (QFX10_02085) | 379943..380530 | + | 588 | WP_280606587.1 | NAD(P)H-dependent oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 366125..399653 | 33528 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 203 a.a. Molecular weight: 24346.12 Da Isoelectric Point: 9.0763
>T279093 WP_280606584.1 NZ_CP123639:c377851-377243 [Ligilactobacillus faecis]
MRAVELLAPLIDDIWNLNERFTLAFAENVDLSRYNFMKLGVSKILEDKELVYNIIPSYTKFINTSRDLIESDLFIYSVQY
NIRYRVKIDDTIYTKLKHYARKEKDLGTLPLDKCLNDIFGVRIILPNARDELSEILALLESKKKQRHIFRYVKRDLEKYH
AVHCYMYPNKHSFPWKLQIWDSRDVQQNTYSHLEHERKREVL
MRAVELLAPLIDDIWNLNERFTLAFAENVDLSRYNFMKLGVSKILEDKELVYNIIPSYTKFINTSRDLIESDLFIYSVQY
NIRYRVKIDDTIYTKLKHYARKEKDLGTLPLDKCLNDIFGVRIILPNARDELSEILALLESKKKQRHIFRYVKRDLEKYH
AVHCYMYPNKHSFPWKLQIWDSRDVQQNTYSHLEHERKREVL
Download Length: 609 bp
Antitoxin
Download Length: 240 a.a. Molecular weight: 27952.94 Da Isoelectric Point: 6.6615
>AT279093 WP_280606583.1 NZ_CP123639:c377240-376521 [Ligilactobacillus faecis]
MIHIVTLAKRDGETFAYHYMTTDKQRFLEMSRKIQNSPEELLASFSVHVISDPSKTFSELQEMDPYFADAILLESFEEFL
TKLSEKQRLTTLDIAAYLFQKYDVTGAFVLQKTLYHIYASYLEKYKKVPFKANFVAFEHGPVDVEVYRANKYHPETLRLS
VEFEKKVFACPYRKELLELVDEIVGRCALQYQGAFASPKKNLTHHKGTPWDRAYARQQNAPILDEDIIKYHYLEHLGES
MIHIVTLAKRDGETFAYHYMTTDKQRFLEMSRKIQNSPEELLASFSVHVISDPSKTFSELQEMDPYFADAILLESFEEFL
TKLSEKQRLTTLDIAAYLFQKYDVTGAFVLQKTLYHIYASYLEKYKKVPFKANFVAFEHGPVDVEVYRANKYHPETLRLS
VEFEKKVFACPYRKELLELVDEIVGRCALQYQGAFASPKKNLTHHKGTPWDRAYARQQNAPILDEDIIKYHYLEHLGES
Download Length: 720 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|