Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1078196..1078852 Replicon chromosome
Accession NZ_CP123607
Organism Serratia marcescens strain RMCH-M16-N

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QFB85_RS05040 Protein ID WP_021504433.1
Coordinates 1078463..1078852 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8G2LCA8
Locus tag QFB85_RS05035 Protein ID WP_004941563.1
Coordinates 1078196..1078459 (+) Length 88 a.a.

Genomic Context


QFB85_RS05035QFB85_RS05040QFB85_RS05015QFB85_RS05020QFB85_RS05025QFB85_RS05030QFB85_RS05045QFB85_RS05050QFB85_RS05055
Location: 1078196..1078459 (264 bp)
Type: Antitoxin
Protein ID: WP_004941563.1
Location: 1078463..1078852 (390 bp)
Type: Toxin
Protein ID: WP_021504433.1
Location: 1073234..1074448 (1215 bp)
Type: Others
Protein ID: WP_015378743.1
Location: 1074617..1075522 (906 bp)
Type: Others
Protein ID: WP_280631311.1
Location: 1075989..1077341 (1353 bp)
Type: Others
Protein ID: WP_280631312.1
Location: 1077520..1077858 (339 bp)
Type: Others
Protein ID: WP_004941561.1
Location: 1078860..1079576 (717 bp)
Type: Others
Protein ID: WP_197753782.1
Location: 1079576..1080958 (1383 bp)
Type: Others
Protein ID: WP_021504432.1
Location: 1080955..1082385 (1431 bp)
Type: Others
Protein ID: WP_280631313.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QFB85_RS05015 (QFB85_05015)1073234..1074448-1215WP_015378743.1D-galactonate dehydratase family protein-
QFB85_RS05020 (QFB85_05020)1074617..1075522-906WP_280631311.1lipid kinase YegS-
QFB85_RS05025 (QFB85_05025)1075989..1077341-1353WP_280631312.1tRNA 5-hydroxyuridine modification protein YegQ-
QFB85_RS05030 (QFB85_05030)1077520..1077858-339WP_004941561.1YegP family protein-
QFB85_RS05035 (QFB85_05035)1078196..1078459+264WP_004941563.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
QFB85_RS05040 (QFB85_05040)1078463..1078852+390WP_021504433.1type II toxin-antitoxin system VapC family toxinToxin
QFB85_RS05045 (QFB85_05045)1078860..1079576-717WP_197753782.1two-component system response regulator BaeR-
QFB85_RS05050 (QFB85_05050)1079576..1080958-1383WP_021504432.1two-component system sensor histidine kinase BaeS-
QFB85_RS05055 (QFB85_05055)1080955..1082385-1431WP_280631313.1multidrug transporter subunit MdtD-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-119)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 14398.63 Da        Isoelectric Point: 8.4983

>T279083 WP_021504433.1 NZ_CP123607:1078463-1078852 [Serratia marcescens]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISSVTEAELRYGVAKRRNKALQSMVEAFLAAVTVYAWDSEAARCYGEM
RANMERKGKIMGAMDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10062.31 Da        Isoelectric Point: 4.6702

>AT279083 WP_004941563.1 NZ_CP123607:1078196-1078459 [Serratia marcescens]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEEE

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References