Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 732096..732765 Replicon chromosome
Accession NZ_CP123607
Organism Serratia marcescens strain RMCH-M16-N

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QFB85_RS03430 Protein ID WP_004931681.1
Coordinates 732343..732765 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag QFB85_RS03425 Protein ID WP_004931679.1
Coordinates 732096..732362 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB85_RS03400 (QFB85_03400) 727408..728409 - 1002 WP_280631232.1 DUF4214 domain-containing protein -
QFB85_RS03405 (QFB85_03405) 728629..729237 - 609 WP_033632167.1 HD domain-containing protein -
QFB85_RS03410 (QFB85_03410) 729421..730095 + 675 WP_021505704.1 hemolysin III family protein -
QFB85_RS03415 (QFB85_03415) 730246..730743 + 498 WP_049186827.1 DUF2165 domain-containing protein -
QFB85_RS03420 (QFB85_03420) 730782..731774 - 993 WP_280631233.1 tRNA-modifying protein YgfZ -
QFB85_RS03425 (QFB85_03425) 732096..732362 + 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
QFB85_RS03430 (QFB85_03430) 732343..732765 + 423 WP_004931681.1 protein YgfX Toxin
QFB85_RS03435 (QFB85_03435) 732831..733349 - 519 WP_280631234.1 flavodoxin FldB -
QFB85_RS03440 (QFB85_03440) 733456..734355 + 900 WP_004931685.1 site-specific tyrosine recombinase XerD -
QFB85_RS03445 (QFB85_03445) 734382..735098 + 717 WP_004931688.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QFB85_RS03450 (QFB85_03450) 735105..736838 + 1734 WP_004931690.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16487.59 Da        Isoelectric Point: 11.0198

>T279081 WP_004931681.1 NZ_CP123607:732343-732765 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEQG

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT279081 WP_004931679.1 NZ_CP123607:732096-732362 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References