Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/PRK09812-MazE
Location 2736285..2736886 Replicon chromosome
Accession NC_018012
Organism Thiocystis violascens DSM 198

Toxin (Protein)


Gene name mazF Uniprot ID I3YBR3
Locus tag THIVI_RS12085 Protein ID WP_014778875.1
Coordinates 2736530..2736886 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID I3YBR2
Locus tag THIVI_RS12080 Protein ID WP_014778874.1
Coordinates 2736285..2736530 (+) Length 82 a.a.

Genomic Context

THIVI_RS12055THIVI_RS12060THIVI_RS12080THIVI_RS12085THIVI_RS12050THIVI_RS12065THIVI_RS12070THIVI_RS12090THIVI_RS12095THIVI_RS12100
Location: 2733256..2733525 (270 bp)
Type: Others
Protein ID: WP_014778871.1
Location: 2733536..2733775 (240 bp)
Type: Others
Protein ID: WP_014778872.1
Location: 2736285..2736530 (246 bp)
Type: Antitoxin
Protein ID: WP_014778874.1
Location: 2736530..2736886 (357 bp)
Type: Toxin
Protein ID: WP_014778875.1
Location: 2731467..2732450 (984 bp)
Type: Others
Protein ID: WP_014778870.1
Location: 2734368..2734595 (228 bp)
Type: Others
Protein ID: WP_052315021.1
Location: 2734592..2735797 (1206 bp)
Type: Others
Protein ID: Protein_2446
Location: 2736996..2738066 (1071 bp)
Type: Others
Protein ID: WP_014778876.1
Location: 2738432..2739307 (876 bp)
Type: Others
Protein ID: WP_014778877.1
Location: 2739409..2740752 (1344 bp)
Type: Others
Protein ID: WP_041446972.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
THIVI_RS120502731467..2732450-984WP_014778870.1IS110 family transposase-
THIVI_RS120552733256..2733525+270WP_014778871.1DUF4160 domain-containing protein-
THIVI_RS120602733536..2733775+240WP_014778872.1DUF2442 domain-containing protein-
THIVI_RS120652734368..2734595-228WP_052315021.1hypothetical protein-
THIVI_RS120702734592..2735797-1206Protein_2446IS3 family transposase-
THIVI_RS120802736285..2736530+246WP_014778874.1growth regulatorAntitoxin
THIVI_RS120852736530..2736886+357WP_014778875.1type II toxin-antitoxin system PemK/MazF family toxinToxin
THIVI_RS120902736996..2738066-1071WP_014778876.1DUF2333 family protein-
THIVI_RS120952738432..2739307-876WP_014778877.1TauD/TfdA family dioxygenase-
THIVI_RS121002739409..2740752-1344WP_041446972.1tetratricopeptide repeat protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--2734592..27356021010


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12782.77 Da        Isoelectric Point: 8.5617

>T27907 WP_014778875.1 NC_018012:2736530-2736886 [Thiocystis violascens DSM 198]
MAYLPNRGDIVHLDFDPSAGREMKGPHFGLVVSGKVFNQQGLAMMCPISQGTAAAARTHGTVVTLMGAGTAIQGAVHCHQ
LKSLDWRARQVRFKEVAPREIVDDVLARVEAILFDRSA

Download         Length: 357 bp

>T27907 NC_018012:2736530-2736886 [Thiocystis violascens DSM 198]
ATGGCGTACCTGCCGAATCGTGGCGACATCGTGCATCTGGATTTCGACCCTTCCGCCGGCCGCGAAATGAAAGGCCCGCA
CTTCGGTCTTGTCGTGAGCGGCAAGGTCTTCAACCAGCAAGGGCTGGCGATGATGTGCCCGATTTCCCAAGGTACTGCGG
CGGCGGCTCGCACCCATGGCACCGTGGTGACGCTGATGGGAGCGGGAACGGCGATCCAGGGAGCCGTTCACTGTCATCAA
TTGAAGTCACTCGACTGGCGTGCGCGGCAGGTCCGCTTCAAGGAGGTTGCGCCGCGAGAGATCGTCGATGACGTCCTGGC
CAGAGTCGAAGCCATTCTGTTTGATCGATCCGCGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8831.17 Da        Isoelectric Point: 4.4865

>AT27907 WP_014778874.1 NC_018012:2736285-2736530 [Thiocystis violascens DSM 198]
MLQTLRKAGGSLVMTVPKAFIDQNALGEGSQVELHLLGRTMTVEAPPRPRYKLADLIAEMPDGLPRVDGWDDMPSVGLEN
D

Download         Length: 246 bp

>AT27907 NC_018012:2736285-2736530 [Thiocystis violascens DSM 198]
ATGCTTCAGACCCTACGCAAAGCCGGTGGCTCGCTCGTGATGACAGTGCCCAAGGCCTTTATTGACCAGAATGCACTGGG
CGAAGGCTCCCAGGTTGAGCTGCATCTTCTTGGCAGGACCATGACGGTCGAAGCGCCACCCCGTCCGCGTTACAAGCTGG
CCGACCTGATCGCCGAGATGCCGGACGGTTTGCCGCGTGTCGACGGTTGGGATGACATGCCCTCGGTCGGACTGGAGAAC
GACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBI3YBR3

Antitoxin

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Source
ID
Structure
AlphaFold DBI3YBR2

References