Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1592982..1593578 Replicon chromosome
Accession NZ_CP123598
Organism Enterobacter cloacae strain RMCH-M23-N

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QFB83_RS07695 Protein ID WP_058684023.1
Coordinates 1593276..1593578 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QFB83_RS07690 Protein ID WP_057072139.1
Coordinates 1592982..1593269 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB83_RS07685 (QFB83_07685) 1591354..1592985 + 1632 WP_013095027.1 Na/Pi cotransporter family protein -
QFB83_RS07690 (QFB83_07690) 1592982..1593269 - 288 WP_057072139.1 putative addiction module antidote protein Antitoxin
QFB83_RS07695 (QFB83_07695) 1593276..1593578 - 303 WP_058684023.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QFB83_RS07700 (QFB83_07700) 1593776..1594645 + 870 WP_023621411.1 23S rRNA pseudouridine(2604) synthase RluF -
QFB83_RS07705 (QFB83_07705) 1594713..1595657 - 945 WP_013095031.1 ketopantoate/pantoate/pantothenate transporter PanS -
QFB83_RS07710 (QFB83_07710) 1595750..1597099 - 1350 WP_013095032.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-93)

Antitoxin

Uncharacterized protein HI1420

(4-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11517.34 Da        Isoelectric Point: 9.9670

>T279068 WP_058684023.1 NZ_CP123598:c1593578-1593276 [Enterobacter cloacae]
MKEIVQTESFRRWEQNLKDRRARTIIASRLFRLANGLAGDIKPVGEGICELRIHFGPGYRIYFKDQGNYIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10040.60 Da        Isoelectric Point: 5.7807

>AT279068 WP_057072139.1 NZ_CP123598:c1593269-1592982 [Enterobacter cloacae]
MHKLTPYDPAIALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSAISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPAGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References