Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3413344..3414013 Replicon chromosome
Accession NZ_CP123597
Organism Serratia marcescens strain RMCH-M26-N

Toxin (Protein)


Gene name cptA Uniprot ID A0A0P0QIF8
Locus tag QFB82_RS16475 Protein ID WP_033632171.1
Coordinates 3413344..3413766 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag QFB82_RS16480 Protein ID WP_004931679.1
Coordinates 3413747..3414013 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB82_RS16455 (QFB82_16455) 3409236..3409754 + 519 WP_004931683.1 flavodoxin FldB -
QFB82_RS16460 (QFB82_16460) 3409789..3411153 - 1365 WP_085337104.1 cell envelope integrity protein CreD -
QFB82_RS16465 (QFB82_16465) 3411234..3412652 - 1419 WP_033632173.1 two-component system sensor histidine kinase CreC -
QFB82_RS16470 (QFB82_16470) 3412649..3413344 - 696 WP_033632172.1 two-component system response regulator CreB -
QFB82_RS16475 (QFB82_16475) 3413344..3413766 - 423 WP_033632171.1 protein YgfX Toxin
QFB82_RS16480 (QFB82_16480) 3413747..3414013 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
QFB82_RS16485 (QFB82_16485) 3414335..3415327 + 993 WP_103086252.1 tRNA-modifying protein YgfZ -
QFB82_RS16490 (QFB82_16490) 3415366..3415863 - 498 WP_280597683.1 DUF2165 domain-containing protein -
QFB82_RS16495 (QFB82_16495) 3416014..3416688 - 675 WP_033632168.1 hemolysin III family protein -
QFB82_RS16500 (QFB82_16500) 3416872..3417480 + 609 WP_004931670.1 HD domain-containing protein -
QFB82_RS16505 (QFB82_16505) 3417521..3418447 - 927 WP_015378971.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16518.60 Da        Isoelectric Point: 10.8114

>T279059 WP_033632171.1 NZ_CP123597:c3413766-3413344 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEES

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT279059 WP_004931679.1 NZ_CP123597:c3414013-3413747 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P0QIF8

Antitoxin

Source ID Structure

References