Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 197077..197611 Replicon plasmid paNv_UK1
Accession NZ_CP123562
Organism Arsenophonus nasoniae strain aNv_UK

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QE193_RS20555 Protein ID WP_135678429.1
Coordinates 197330..197611 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE193_RS20550 Protein ID WP_135678431.1
Coordinates 197077..197343 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE193_RS20525 (QE193_20535) 192132..193100 - 969 WP_135678441.1 DUF2184 domain-containing protein -
QE193_RS20530 (QE193_20540) 193104..193541 - 438 WP_246067492.1 hypothetical protein -
QE193_RS20535 (QE193_20545) 193583..194770 - 1188 WP_135678437.1 DUF2213 domain-containing protein -
QE193_RS20540 (QE193_20550) 194757..195635 - 879 WP_167876731.1 phage minor head protein -
QE193_RS20545 (QE193_20555) 195592..196779 - 1188 WP_280622536.1 DUF1073 domain-containing protein -
QE193_RS20550 (QE193_20560) 197077..197343 + 267 WP_135678431.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QE193_RS20555 (QE193_20565) 197330..197611 + 282 WP_135678429.1 type II toxin-antitoxin system YafQ family toxin Toxin
QE193_RS20560 (QE193_20570) 197699..198304 - 606 WP_135678426.1 recombinase family protein -
QE193_RS20565 (QE193_20575) 198505..198768 - 264 WP_246067491.1 hypothetical protein -
QE193_RS20570 (QE193_20580) 199320..200210 - 891 WP_246067489.1 transposase -
QE193_RS20575 (QE193_20585) 200321..200932 + 612 Protein_262 IS21 family transposase -
QE193_RS20580 (QE193_20590) 200997..202155 - 1159 Protein_263 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..220475 220475


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10884.58 Da        Isoelectric Point: 10.4639

>T279042 WP_135678429.1 NZ_CP123562:197330-197611 [Arsenophonus nasoniae]
MRTIERSVTFKRDYKREAKGRHRNNLDKVLISVITSLVIDEPLKTSHRDHDLIGKWSGHRECHIKPDLLLIYRKPDSETL
QLVRLGSHAQLFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9816.24 Da        Isoelectric Point: 6.4627

>AT279042 WP_135678431.1 NZ_CP123562:197077-197343 [Arsenophonus nasoniae]
MRHSETYVRARIDANTKQRATAALEAMGLSVSDAIRLLMLRVADEQRLPFDVKVPNTTTKKAIAELEEGKGKQFDCVTAL
MADLHEDN

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References