Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2641405..2642059 Replicon chromosome
Accession NZ_CP123561
Organism Arsenophonus nasoniae strain aNv_UK

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag QE193_RS13735 Protein ID WP_026821813.1
Coordinates 2641405..2641812 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE193_RS13740 Protein ID WP_026821812.1
Coordinates 2641793..2642059 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE193_RS13715 (QE193_13720) 2637089..2637829 + 741 WP_280622420.1 transposase zinc-binding domain-containing protein -
QE193_RS13720 (QE193_13725) 2637876..2638286 + 411 WP_280622421.1 transposase -
QE193_RS13725 (QE193_13730) 2639071..2640384 + 1314 WP_051296926.1 S8 family serine peptidase -
QE193_RS13730 (QE193_13735) 2640871..2641389 + 519 WP_026821814.1 flavodoxin FldB -
QE193_RS13735 (QE193_13740) 2641405..2641812 - 408 WP_026821813.1 protein YgfX Toxin
QE193_RS13740 (QE193_13745) 2641793..2642059 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE193_RS13745 (QE193_13750) 2642319..2643305 + 987 WP_051296925.1 tRNA-modifying protein YgfZ -
QE193_RS13750 (QE193_13755) 2644160..2644399 - 240 WP_026821810.1 hypothetical protein -
QE193_RS13755 (QE193_13760) 2644727..2645563 - 837 WP_026821809.1 hypothetical protein -
QE193_RS13760 (QE193_13765) 2645655..2646512 - 858 WP_026821808.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279039 WP_026821813.1 NZ_CP123561:c2641812-2641405 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279039 WP_026821812.1 NZ_CP123561:c2642059-2641793 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References