Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 27379..27913 Replicon plasmid paNv_CH7
Accession NZ_CP123551
Organism Arsenophonus nasoniae strain aNv_CH

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QE197_RS24385 Protein ID WP_135678429.1
Coordinates 27632..27913 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE197_RS24380 Protein ID WP_135678431.1
Coordinates 27379..27645 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE197_RS24355 (QE197_24340) 22438..23406 - 969 WP_280622704.1 DUF2184 domain-containing protein -
QE197_RS24360 (QE197_24345) 23410..23751 - 342 WP_280631973.1 hypothetical protein -
QE197_RS24365 (QE197_24350) 23888..25072 - 1185 WP_135678485.1 DUF2213 domain-containing protein -
QE197_RS24370 (QE197_24355) 25059..25937 - 879 WP_167876731.1 phage minor head protein -
QE197_RS24375 (QE197_24360) 25894..27090 - 1197 WP_280632041.1 DUF1073 domain-containing protein -
QE197_RS24380 (QE197_24365) 27379..27645 + 267 WP_135678431.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QE197_RS24385 (QE197_24370) 27632..27913 + 282 WP_135678429.1 type II toxin-antitoxin system YafQ family toxin Toxin
QE197_RS24390 (QE197_24375) 28001..28603 - 603 WP_280622711.1 recombinase family protein -
QE197_RS24395 (QE197_24380) 28731..29957 - 1227 WP_135678495.1 PBSX family phage terminase large subunit -
QE197_RS24400 (QE197_24385) 29935..30522 - 588 WP_026824067.1 hypothetical protein -
QE197_RS24405 (QE197_24390) 30785..31780 - 996 WP_167876733.1 tyrosine-type recombinase/integrase -
QE197_RS24410 (QE197_24395) 31854..32267 - 414 WP_135678499.1 hypothetical protein -
QE197_RS24415 (QE197_24400) 32302..32757 - 456 WP_280622712.1 lysis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..42415 42415
- flank IS/Tn - - 28001..28603 602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10884.58 Da        Isoelectric Point: 10.4639

>T279037 WP_135678429.1 NZ_CP123551:27632-27913 [Arsenophonus nasoniae]
MRTIERSVTFKRDYKREAKGRHRNNLDKVLISVITSLVIDEPLKTSHRDHDLIGKWSGHRECHIKPDLLLIYRKPDSETL
QLVRLGSHAQLFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9816.24 Da        Isoelectric Point: 6.4627

>AT279037 WP_135678431.1 NZ_CP123551:27379-27645 [Arsenophonus nasoniae]
MRHSETYVRARIDANTKQRATAALEAMGLSVSDAIRLLMLRVADEQRLPFDVKVPNTTTKKAIAELEEGKGKQFDCVTAL
MADLHEDN

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References