279031

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2640431..2641085 Replicon chromosome
Accession NZ_CP123544
Organism Arsenophonus nasoniae strain aNv_CH

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag QE197_RS13830 Protein ID WP_026821813.1
Coordinates 2640431..2640838 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE197_RS13835 Protein ID WP_026821812.1
Coordinates 2640819..2641085 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE197_RS13815 (QE197_13815) 2636114..2637313 + 1200 WP_135677934.1 IS91 family transposase -
QE197_RS13820 (QE197_13820) 2638097..2639410 + 1314 WP_051296926.1 S8 family serine peptidase -
QE197_RS13825 (QE197_13825) 2639897..2640415 + 519 WP_026821814.1 flavodoxin FldB -
QE197_RS13830 (QE197_13830) 2640431..2640838 - 408 WP_026821813.1 protein YgfX Toxin
QE197_RS13835 (QE197_13835) 2640819..2641085 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE197_RS13840 (QE197_13840) 2641345..2642331 + 987 WP_051296925.1 tRNA-modifying protein YgfZ -
QE197_RS13845 (QE197_13845) 2643186..2643425 - 240 WP_026821810.1 hypothetical protein -
QE197_RS13850 (QE197_13850) 2643753..2644589 - 837 WP_026821809.1 hypothetical protein -
QE197_RS13855 (QE197_13855) 2644681..2645538 - 858 WP_026821808.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279031 WP_026821813.1 NZ_CP123544:c2640838-2640431 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279031 WP_026821812.1 NZ_CP123544:c2641085-2640819 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References