Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 75389..75923 Replicon plasmid paNv_CAN1
Accession NZ_CP123524
Organism Arsenophonus nasoniae strain aNv_CAN

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QE258_RS21280 Protein ID WP_135678429.1
Coordinates 75389..75670 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE258_RS21285 Protein ID WP_135678431.1
Coordinates 75657..75923 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE258_RS21255 (QE258_21260) 70845..72003 + 1159 Protein_102 IS3 family transposase -
QE258_RS21260 (QE258_21265) 72020..72679 - 660 Protein_103 IS21 family transposase -
QE258_RS21265 (QE258_21270) 72790..73680 + 891 WP_246067489.1 transposase -
QE258_RS21270 (QE258_21275) 74232..74495 + 264 WP_246067491.1 hypothetical protein -
QE258_RS21275 (QE258_21280) 74696..75301 + 606 WP_135678426.1 recombinase family protein -
QE258_RS21280 (QE258_21285) 75389..75670 - 282 WP_135678429.1 type II toxin-antitoxin system YafQ family toxin Toxin
QE258_RS21285 (QE258_21290) 75657..75923 - 267 WP_135678431.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QE258_RS21290 (QE258_21295) 76128..77408 + 1281 WP_280632492.1 DUF1073 domain-containing protein -
QE258_RS21295 (QE258_21300) 77365..78243 + 879 WP_167876731.1 phage minor head protein -
QE258_RS21300 (QE258_21305) 78230..79417 + 1188 WP_135678437.1 DUF2213 domain-containing protein -
QE258_RS21305 (QE258_21310) 79459..79896 + 438 WP_246067492.1 hypothetical protein -
QE258_RS21310 (QE258_21315) 79900..80868 + 969 WP_135678441.1 DUF2184 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..226576 226576


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10884.58 Da        Isoelectric Point: 10.4639

>T279026 WP_135678429.1 NZ_CP123524:c75670-75389 [Arsenophonus nasoniae]
MRTIERSVTFKRDYKREAKGRHRNNLDKVLISVITSLVIDEPLKTSHRDHDLIGKWSGHRECHIKPDLLLIYRKPDSETL
QLVRLGSHAQLFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9816.24 Da        Isoelectric Point: 6.4627

>AT279026 WP_135678431.1 NZ_CP123524:c75923-75657 [Arsenophonus nasoniae]
MRHSETYVRARIDANTKQRATAALEAMGLSVSDAIRLLMLRVADEQRLPFDVKVPNTTTKKAIAELEEGKGKQFDCVTAL
MADLHEDN

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References