Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2753720..2754374 Replicon chromosome
Accession NZ_CP123523
Organism Arsenophonus nasoniae strain aNv_CAN

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag QE258_RS14655 Protein ID WP_026821813.1
Coordinates 2753720..2754127 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE258_RS14660 Protein ID WP_026821812.1
Coordinates 2754108..2754374 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE258_RS14640 (QE258_14645) 2749406..2750353 + 948 WP_280632308.1 IS91 family transposase -
QE258_RS14645 (QE258_14650) 2751386..2752699 + 1314 WP_051296926.1 S8 family serine peptidase -
QE258_RS14650 (QE258_14655) 2753186..2753704 + 519 WP_026821814.1 flavodoxin FldB -
QE258_RS14655 (QE258_14660) 2753720..2754127 - 408 WP_026821813.1 protein YgfX Toxin
QE258_RS14660 (QE258_14665) 2754108..2754374 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE258_RS14665 (QE258_14670) 2754634..2755620 + 987 WP_051296925.1 tRNA-modifying protein YgfZ -
QE258_RS14670 (QE258_14675) 2756475..2756714 - 240 WP_026821810.1 hypothetical protein -
QE258_RS14675 (QE258_14680) 2757042..2757878 - 837 WP_026821809.1 hypothetical protein -
QE258_RS14680 (QE258_14685) 2757970..2758827 - 858 WP_026821808.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279023 WP_026821813.1 NZ_CP123523:c2754127-2753720 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279023 WP_026821812.1 NZ_CP123523:c2754374-2754108 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References