Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 25067..25601 Replicon plasmid paPv8
Accession NZ_CP123512
Organism Arsenophonus nasoniae strain aPv

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QE210_RS20965 Protein ID WP_135678429.1
Coordinates 25320..25601 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE210_RS20960 Protein ID WP_280627049.1
Coordinates 25067..25333 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE210_RS20935 (QE210_20840) 20122..21090 - 969 WP_280626642.1 DUF2184 domain-containing protein -
QE210_RS20940 (QE210_20845) 21094..21573 - 480 WP_280627040.1 hypothetical protein -
QE210_RS20945 (QE210_20850) 21573..22760 - 1188 WP_280627101.1 DUF2213 domain-containing protein -
QE210_RS20950 (QE210_20855) 22747..23625 - 879 WP_280627045.1 phage minor head protein -
QE210_RS20955 (QE210_20860) 23582..24964 - 1383 WP_280627047.1 DUF1073 domain-containing protein -
QE210_RS20960 (QE210_20865) 25067..25333 + 267 WP_280627049.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QE210_RS20965 (QE210_20870) 25320..25601 + 282 WP_135678429.1 type II toxin-antitoxin system YafQ family toxin Toxin
QE210_RS20970 (QE210_20875) 25668..26273 - 606 WP_180560436.1 recombinase family protein -
QE210_RS20975 (QE210_20880) 26401..27834 - 1434 WP_280627053.1 phage terminase large subunit -
QE210_RS20980 (QE210_20885) 27834..28427 - 594 WP_280627054.1 hypothetical protein -
QE210_RS20985 (QE210_20890) 28690..29685 - 996 WP_280627055.1 tyrosine-type recombinase/integrase -
QE210_RS20990 (QE210_20895) 29770..30297 - 528 WP_280627057.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..40135 40135
- flank IS/Tn - - 25668..26273 605


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-79)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10884.58 Da        Isoelectric Point: 10.4639

>T279022 WP_135678429.1 NZ_CP123512:25320-25601 [Arsenophonus nasoniae]
MRTIERSVTFKRDYKREAKGRHRNNLDKVLISVITSLVIDEPLKTSHRDHDLIGKWSGHRECHIKPDLLLIYRKPDSETL
QLVRLGSHAQLFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9800.18 Da        Isoelectric Point: 6.4689

>AT279022 WP_280627049.1 NZ_CP123512:25067-25333 [Arsenophonus nasoniae]
MRHSETYVRARIDANTKQRATAALEAMGLSVSDAIRLLMLRVADEQRLPFDVKVPNTTTKKAIAELEEGKGKQFDSVTAL
MADLHEDN

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References